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Induktion von atherosklerotischen Plaques durch Aktivierung von Mineralocorticoid-Rezeptoren im Apolipoprotein E-defizienten Mäusen
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Induktion von atherosklerotischen Plaques durch Aktivierung von Mineralocorticoid-Rezeptoren im Apolipoprotein E-defizienten Mäusen

Article DOI: 10.3791/58303-v • 07:36 min • September 26th, 2018
September 26th, 2018 •
1, 1, 1, 1, 1,2
1Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele Pisana, Rome, Italy, 2Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Rome, Italy

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Wir beschreiben ein Protokoll zur Atherosklerose in die Aortenwurzel von ApoE- / - Mäusen gefüttert mit einem atherogenen Diät durch eine kontinuierliche Freisetzung von Aldosteron zu induzieren. Methoden zur Charakterisierung von Plaque Zusammensetzung werden ebenfalls beschrieben.

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Medizin Ausgabe 139 Atherosklerose Aldosteron Entzündung ApoE- / - Aortenwurzel immunohistochemistry
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