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JoVE Journal Cancer Research
Kvantificering af hjernen metastatisk tumor mikro-miljø ved hjælp af en organ-on-a chip 3D-model, machine learning, og konfokal tomografi
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Kvantificering af hjernen metastatisk tumor mikro-miljø ved hjælp af en organ-on-a chip 3D-model, machine learning, og konfokal tomografi

Article DOI: 10.3791/61654-v • 09:53 min • August 16th, 2020
August 16th, 2020 •
*1,2, *1,2, 2,3,4, 1,2
1Department of Internal Medicine, University of Michigan Ann Arbor, 2Rogel Cancer Center, University of Michigan Ann Arbor, 3Department of Neurosurgery, University of Michigan Ann Arbor, 4Department of Cell and Developmental Biology, University of Michigan Ann Arbor
* These authors contributed equally

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Her præsenterer vi en protokol for forberedelse og dyrkning af en blod-hjerne barriere metastatisk tumor mikro-miljø og derefter kvantificere sin tilstand ved hjælp af konfokale billeddannelse og kunstig intelligens (machine learning).

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Kræftforskning Tumor mikromiljø kræft organ-on-a-chip machine learning kunstig intelligens konfokal mikroskopi langsigtet cellekultur
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