JoVE Neuroscience is a multidisciplinary section devoted to investigations of the structure, function, physiology, and pathophysiology of the brain and nervous system. Included methodologies range from molecular and cellular level studies to full central and peripheral neural systems. Potential treatment platforms and surgical techniques for neurological diseases and disorders are also presented in this section.

Neuroscience

JoVE Medicine serves as a connection between basic research and clinical applications. Articles may present medical procedures, case studies or clinical trial methodologies. Included studies are often modeled towards predictive, preventative, personalized, and practical approaches to treatment of disease. The goal of research methodologies in this section is to improve overall patient care and prognosis.

Medicine

JoVE Immunology and Infection includes content from a variety of fields working toward a shared initiative of improving global health. Techniques evaluating the biological response to pathogens from the molecular to organismal level are presented as well as therapeutic agents and their efficacy in treating disease.

Immunology and Infection

JoVE Genetics publishes video articles demonstrating experimental approaches to investigate gene function and regulation. This includes methods to study gene expression, mutagenesis, epigenetics, genetic determinants of development, genetic disorders, population genetics and evolution.

Genetics

JoVE Environment is dedicated to research methodologies that address environmental concerns and seek to better understand Earth's ecosystem.  Special consideration is given to experimental methodologies that assess society’s impact on the environment, suggest solutions for protecting Earth’s resources, and develop sustainable fuel sources. Moving towards an environmentally conscious planet is a collaborative effort with contributions from both life and physical scientists.

Environment

JoVE Engineering encompasses a broad range of experimental and instrumental techniques utilized in physics research. Investigations in this area strive to address and answer a broad range of scientific questions, such as device mechanisms and efficiencies, using physical tools. This approach often requires a combination of specialties, and research in this area tends to be interdisciplinary with contributions from mechanical, electrical, and chemical engineers.

Engineering

JoVE Developmental Biology publishes research methodologies in the field of developmental biology. This includes methods that are used to study biological development in vitro and in vivo at the molecular, cellular, tissue, organ and whole organism levels.

Developmental Biology

JoVE Chemistry surveys a broad scope of chemical disciplines. This collection includes fundamental and applied research that investigates molecular interactions, properties, and structure spanning in the following core divisions: analytical, organic, organometallic, inorganic, bioinorganic, and biochemistry. This section also includes the design and preparation of materials and small molecules for advanced or unique applications.

Chemistry

JoVE Cancer Research illustrates experimental approaches in biomedical research and clinical practice aimed at understanding, detecting, treating and preventing cancer. The video articles in this section demonstrate methods to study the cellular and molecular mechanisms of cancer, animal models of cancer research, development of new therapies and diagnostics, tumor imaging, chemical and radiation treatments, surgical procedures and improvements in therapy. These video articles offer researchers and clinical practitioners an efficient way to learn the technologies and experimental methods in cancer research.

Cancer Research

JoVE Biology welcomes all general biology research methodologies. Content in this section canvases all fields of cell, molecular, and organismal biology, ranging from new applications of standard techniques to novel approaches aimed at understanding the functions of life and living organisms. This diverse section includes, but is not limited to, techniques in physical biology, cellular biochemistry, genetics, physiology, systems biology and a combination of eukaryotic and prokaryotic model systems.

Biology

JoVE Bioengineering merges both physical and life sciences to understand and predict biological processes. Applying physical science tools to life science questions allow for the discovery of better technologies to measure, diagnose, and clinically treat disease.

Bioengineering

JoVE Biochemistry publishes experiments that investigate the structure, function, and interactions of biological molecules. The video articles in this section demonstrate methods to study nucleic acids, proteins, carbohydrates and lipids as well as enzyme function, protein folding, molecular interactions and biochemical reactions.

Biochemistry

JoVE Behavior documents observational and experimental techniques that seek to understand human and animal behavior. Work in this field includes analysis of genetic causes and physiological responses to internal or external stimuli as well as the implicated brain regions.

Behavior

This protocol establishes a behavioral phenotyping paradigm in MPTP-treated zebrafish larvae to evaluate Parkinson's disease-like motor and non-motor deficits.

Phenotypic Profiling of MPTP-Induced Parkinsonian-like Behavioral Phenotypes in Zebrafish Larvae Based on Behavioral Experiment

This protocol introduces an automated sound localization testing system with precise loudspeaker placement and integrated response analysis, validated in normal-hearing participants and participants with single-sided deafness. It provides a reproducible method to assess spatial hearing and supports functional classification using the International Classification of Functioning, Disability and Health (ICF) framework.

An Automated System for Sound Localization Testing in Hearing-Impaired Listeners

In the context of the virtual celebrity experience, content quality most strongly drives satisfaction; satisfaction, in turn, increases purchase intention indirectly via loyalty. Personalization strengthens the satisfaction-loyalty link, so firms should prioritize emotion-evoking, narrative-consistent virtual celebrity content and personalized loyalty programs.

How Virtual Celebrity Characteristics Drive Purchase Intention: Testing the Stimulus-Organism-Response Framework with Structural Equation Modeling

Gases that seem harmless at atmospheric pressure can induce behaviors like narcosis under hyperbaric conditions. Conventional hyperbaric pressure chambers are costly and labor-intensive. This study presents a straightforward, low-cost method for examining xenon's effects on Drosophila melanogaster at moderate pressures below 4 atm.

Validation of Hyperbaric Pressure System with Xenon Anesthesia for <em>Drosophila melanogaster</em>

We present an open-source virtual agent platform for conducting real-time motivational interviews, combining state-of-the-art language and diffusion models to adapt to users' behavior and profile. Utilizing the Greta 2.0 platform, it supports various topics, including nutrition and sport-focused interventions, and offers a flexible, validated tool for enhancing digital therapeutic interactions.

Virtual Agent for Real-Time Motivational Interviewing by Integrating Adaptive Nonverbal Behavior and Language Models

This protocol describes the use of physiological indicators to measure variations in cognitive load across different task difficulty levels in human-AI collaborative tasks. The findings suggest that people adapt their decision-making processes according to task difficulty, thereby reflecting different levels of cognitive load.

Estimate the Cognitive Load Using Electrocardiographic Measure: A Human-AI Collaborative Task

This protocol introduces vmTracking, a method that enables high-accuracy pose tracking in videos of multiple freely moving, markerless animals, even under crowded conditions where animals are densely grouped. This approach provides reliable data for analyzing social interactions that occur in semi-natural environments where animals can move freely.

Utilizing vmTracking to Improve the Accuracy of Multi-Animal Pose Estimation in Rodent Social Behavior Studies

This study established cough and sneeze models in mice by applying specific stimuli to the trachea and nasal cavity, and developed an audio-based method to distinguish between mouse coughs and sneezes by analyzing differences in their acoustic signals.<br...

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice

This study proposed an experimental paradigm that applies High-Definition Transcranial Direct Current Stimulation (HD-tDCS) to improve human metacognition in human-AI delegation tasks. The results demonstrated the effectiveness of HD-tDCS in enhancing metacognitive sensitivity.

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity

This paper outlines the protocol for qualitatively and quantitatively validating a university service-learning instrument, following the parsimony criterion to create the most robust and optimal version possible. The Delphi qualitative validation method and Robust Unweighted Least Squares Exploratory Factor Analysis, as a quantitative item optimization method, are utilized for this purpose.

Journal - Behavior