Isthmus
Isthmus - Related Videos
08:09
Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
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Cited by 11 •
2017
We explored a tubal cytologic method by sampling the fallopian tube directly post-surgical excision as a tool of ovarian cancer early detection. Here, we present a protocol to collect fallopian tube cells from freshly received surgical specimens.
03:02
Orthotopic Inoculation of Thyroid Cancer Cells into Murine Thyroid: A Procedure to Establish Orthotopic Thyroid Cancer Mouse Model
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2023
This video describes the procedure for orthotopic inoculation of thyroid cancer cells into the thyroid gland of mouse models, which may then serve as a valuable platform to assess carcinogenesis and discover potential treatment strategies.
15:58
Using Point of Care Ultrasound to Augment Acquisition of Physical Exam Skills: Organs
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2023
Source: Joseph H. Donroe, Rachel Liu; Yale School of Medicine, USA Point of care ultrasound (POCUS) is used by clinicians for diagnosis, ongoing monitoring, and/or procedural guidance at the time of patient care. Many medical schools are now teaching POCUS as a part of their basic clinical skills training, in addition to history, physical exams, and clinical reasoning. Besides being an independent skill, POCUS is also an incredibly useful tool for augmenting the teaching and learning of the...
08:09
CUBIC Protocol Visualizes Protein Expression at Single Cell Resolution in Whole Mount Skin Preparations
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Cited by 9 •
2016
This report describes a CUBIC protocol to clarify full thickness mouse skin biopsies, and visualize protein expression patterns, proliferating cells, and sebocytes at the single cell resolution in 3D. This method enables accurate assessment of skin anatomy and pathology, and of abnormal epidermal phenotypes in genetically modified mouse lines.
05:21
Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
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2025
Here, we introduce a novel approach-Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri. A laparoscopic extracorporeal knot-pusher is used to perform cervical cerclage, achieving complete occlusion of uterine arteries. Thereafter, the corpus uteri are excised to enhance visibility and facilitate the operative field.
FAQs
A narrowed connection can channel the movement of fluids, cells, or nerve signals between larger regions. Its geometry may therefore influence how efficiently material or information passes from one compartment to another, while also marking the transition between anatomically distinct areas. This makes the shape of an isthmus relevant when interpreting organ function and internal organization.
The tissues forming an isthmus can provide structural support and may regulate transport, signaling, or exchange between connected regions. Consequently, the bridge can contribute actively to coordinated function rather than merely maintaining continuity. Examining its tissue properties helps relate the visible junction to the physiological interactions occurring across or around it.
Identifying an isthmus highlights how a larger biological structure is divided into neighboring compartments while remaining continuous. This spatial information supports descriptions of organ organization and developmental patterning, especially where a constricted junction separates regions with distinct identities. The feature can therefore serve as an anatomical landmark for comparing structure across specimens or stages.
Researchers can assess whether a narrow region maintains tissue continuity between two larger areas, separates recognizable compartments, and has a geometry that could channel transport or signaling. They should also consider the tissues forming the junction and any visible variation. These observations help distinguish an isthmus from a simple boundary or an unrelated constriction.
The thyroid and uterine isthmuses show how the same anatomical principle can appear in different organs. Each example helps investigators describe the relationship between connected regions while considering local tissue organization and function. They are useful in anatomy, comparative studies, imaging, and discussions of how junctions contribute to organ structure.
Changes at an isthmus can affect the relationship between adjacent compartments and may alter normal transport, signaling, exchange, or structural continuity. For that reason, variation or disease at these junctions can influence interpretation in imaging and anatomy and may be important during clinical procedures. Recognizing the site supports more precise description of altered organ organization.