Erectile Tissue
Erectile Tissue - Related Videos
08:03
Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
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Cited by 14 •
2018
Intracavernosal pressure recording (ICP) is an important method to evaluate the erectile function of experimental animals. Here, a detailed protocol is demonstrated for the recording procedure of ICP by catheterizing the crura penis and then electrically stimulating the cavernous nerves in rats.
04:22
Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
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Cited by 2 •
2025
An integrated treatment model for unconsummated marriage (UCM) due to psychogenic erectile dysfunction is presented, offering streamlined management from assessment to intervention. Emphasizing patient-centered care and communication, preliminary results show improved success rates and satisfaction, supporting its effectiveness in addressing infertility in UCM from the male perspective.
09:49
Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
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Cited by 3 •
2021
Precise disclosure of methods and protocols is crucial for large scale uptake of stem cell therapies. Here, we present a protocol to isolate adipose-derived regenerative cells, used for a single intracavernous injection as treatment of erectile dysfunction (ED) following radical prostatectomy (RP).
07:48
Working with Human Tissues for Translational Cancer Research
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Cited by 4 •
2015
Translational cancer research is dependent on extraction of human tissues. Much work has gone into optimizing extraction methods for ex vivo analysis. Here, we describe tissue processing methods allowing for maximal data output from limited samples.
11:12
Tissue Engineering of a Human 3D in vitro Tumor Test System
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Cited by 34 •
2013
Methods to create human 3D tumor tissues as test systems are described. These technologies are based on a decellularized Biological Vascularized Scaffold (BioVaSc), primary human cells and a tumor cell line, which can be cultured under static as well as under dynamic conditions in a flow bioreactor.
FAQs
Nitric oxide acts as a signaling molecule that relaxes smooth muscle in arterial walls and erectile bodies. This relaxation increases the space available for blood to enter, linking nerve activity to a vascular response. Studying this pathway helps explain how neural signals can produce controlled changes in tissue firmness and blood flow.
Increased blood inflow expands the internal vascular spaces, which can compress nearby veins. This limits blood leaving the tissue and helps sustain engorgement rather than allowing the response to end immediately. The mechanism shows that erectile function depends on coordinated control of both incoming arterial flow and outgoing venous drainage.
Nerve signals initiate the response by promoting nitric oxide release, while smooth muscle relaxation changes the diameter and capacity of vascular pathways. Blood vessels then deliver increased inflow to the erectile bodies, and expanded spaces affect venous outflow. This interaction illustrates how neural, vascular, and muscular systems jointly regulate a physiological response.
Disruption can occur when nitric oxide release, smooth-muscle relaxation, arterial blood inflow, or venous compression does not function effectively. Because these steps are connected, a problem in one part of the pathway may affect the overall response. This framework helps biological research relate erectile dysfunction and vascular disease to underlying regulatory mechanisms.
Researchers can examine how arousal-related nerve signals coordinate nitric oxide release, smooth-muscle relaxation, vascular filling, and venous compression. Following these linked events provides a way to study reproductive physiology as an interaction among several body systems. The resulting knowledge helps clarify how blood-flow regulation supports sexual function across relevant body structures.
Its response provides a biologically meaningful context for examining blood-vessel behavior and smooth-muscle signaling. Investigators can use the pathway from neural stimulation to nitric oxide release, increased inflow, and tissue engorgement to consider where regulation may fail. This connects reproductive physiology with broader research on vascular function and related disorders.