Ablation Procedures

Ablation procedures are minimally invasive or surgical treatments that deliberately destroy, remove, or isolate abnormal tissue to relieve symptoms or treat disease. They work by delivering controlled energy or agents, such as heat, cold, electrical current, laser energy, or chemicals, to produce tissue injury while limiting damage to surrounding structures. In medicine, clinicians use ablation to treat cardiac arrhythmias, certain tumors, chronic pain, and other localized conditions, often with catheter-based or image-guided techniques. By targeting disease at its source, these procedures can reduce symptoms, preserve healthy tissue, and offer alternatives to more extensive surgery, although outcomes depend on accurate targeting and appropriate patient selection.

Ablation Procedures - Related Videos

Research

JoVE Journal - Medicine
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Remote Magnetic Navigation for Accurate, Real-time Catheter Positioning and Ablation in Cardiac Electrophysiology Procedures

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Cited by 51 •

2013

This report provides a detailed description of a new remote navigation system based on magnetic driven forces, which has been recently introduced as a new robotic tool for human cardiac electrophysiology procedures.

Research

JoVE Journal - Medicine
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Focal Laser Ablation of Prostate Cancer: An Office Procedure

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Cited by 3 •

2021

This article presents and describes an outpatient treatment for prostate cancer using focal laser ablation. Laser catheter placement is guided by MRI-ultrasound fusion imaging in a fashion similar to prostate needle biopsy. Treatment is monitored in real-time with a thermal probe, placed adjacent to the laser fiber.

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JoVE Journal - Medicine
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Robotic Ablation of Atrial Fibrillation

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Cited by 12 •

2015

Pulmonary vein isolation (PVI) with an ablation catheter is a curative treatment for atrial fibrillation (AF). Robotic catheter systems aim to improve catheter steerability. Here, a procedure with a new robotic catheter system is presented. The goal of the procedure is electrical block between pulmonary vein and left atrium.

Research

JoVE Journal - Medicine
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Thermal Ablation for the Treatment of Abdominal Tumors

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Cited by 19 •

2011

A thermal tumor ablation procedure is described. The entire procedure is detailed, including pretreatment planning and imaging studies, anesthesia, adjuvant techniques to facilitate a percutaneous approach, imaging guidance of the ablation device to the tumor, thermal treatment, post-treatment care and follow-up.

Research

JoVE EoE - Neuroimaging

Targeted Neuronal Ablation Using Two-Photon Microscopy in a Zebrafish Larava

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2025

Source: Muto, A., et al. Ablation of a Neuronal Population Using a Two-photon Laser and Its Assessment Using Calcium Imaging and Behavioral Recording in Zebrafish Larvae. J. Vis. Exp. (2018) In this video, a two-photon laser ablation procedure is demonstrated, enabling the selective destruction of fluorescent neurons in agarose-immobilized zebrafish larvae. High-resolution imaging before and after the procedure confirms efficient neuronal damage, as observed by the absence of fluorescence.

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