Donor Aorta Dissection
Donor Aorta Dissection - Related Videos
12:13
Ex Situ Normothermic Machine Perfusion of Donor Livers
0 Views •
Cited by 21 •
2015
Here we present a protocol describing oxygenated ex situ machine perfusion of donor liver grafts. This article contains a step by step protocol to procure and prepare the liver graft for machine perfusion, prepare the perfusion fluid, prime the perfusion machine and perform oxygenated normothermic machine perfusion of the liver graft.
03:13
Porcine Aorta Isolation: A Surgical Procedure to Excise the Thoracic Aorta From Miniature Pigs for Downstream Analysis
0 Views •
2025
In this video, we demonstrate a procedure for the surgical removal of the aorta from miniature pigs. Endothelial cells harvested from these isolated aortae can be further cultured in in vitro conditions to study coagulation and immune responses.
07:17
Single Port Donor Nephrectomy
0 Views •
Cited by 5 •
2011
Single port laparoscopic surgery is changing the standard of care in surgical care like nothing since the laparoscopic technique was introduced 20 years ago. We present out technique of single port donor nephrectomy using the Gelpoint device. We have successfully performed this surgery in 100 patients.
03:51
Exposing Infrarenal Abdominal Aorta in Porcine Model: A Surgical Procedure to Access Porcine Infrarenal Abdominal Aorta for Further Studies
0 Views •
2025
This video demonstrates the surgical procedure to locate and dissect the infrarenal aorta from the surrounding tissues for accessing it. The exposed aorta can be used for further studies.
15:15
Flow Cytometry Analysis of Immune Cells Within Murine Aortas
0 Views •
Cited by 87 •
2011
This paper presents a flow cytometry-based method to investigate the immune composition of aortas. The paper also illustrates an additional technique that allows examining surrounding adventitia and vessel wall separately. This method opens possibilities to perform phenotypical analyses of aortic leukocytes and apply several immunological assays for atherosclerosis studies.
FAQs
The intimal defect provides an entry route for blood or preservation fluid into the aortic wall. Once material tracks within the media, it can extend along the vessel rather than remaining confined to the original injury. This creates a false channel whose length and location may influence wall integrity, graft suitability, and the technical difficulty of later reconstruction or implantation.
The media contributes to the structural strength of the aortic wall. Separation within this layer can weaken the vessel and may compromise its ability to tolerate handling, suturing, or physiologic pressure after implantation. For transplant teams, this concern is relevant because an apparently usable segment may carry a higher risk of anastomotic failure or other vascular complications.
A false channel within the aortic wall can alter the space available for flow or extend near branch origins. If a branch artery becomes obstructed, the associated graft territory may receive inadequate perfusion. This makes the location of the dissection important during donor evaluation and surgical planning, particularly when vascular branches are needed to supply the transplanted organ.
Assessment can occur during donor evaluation, vascular procurement, graft preparation, and implantation. Examining the vessel at more than one stage helps identify abnormalities that may become clearer after procurement or handling. Findings can then inform tissue selection, determine whether the graft is appropriate for use, and alert the surgical team to possible vascular hazards before completion of the reconstruction.
Careful inspection helps identify wall separation, the apparent extent of the affected segment, and possible involvement of branch arteries. These observations support decisions about whether tissue should be selected, modified, or avoided. In practice, inspection links the anatomic finding to recipient safety by allowing the team to anticipate impaired graft perfusion and anastomotic problems.
The finding may change which vascular tissue is selected and how the graft is prepared or implanted. Surgeons must account for potential wall weakness, false-channel extension, and branch obstruction when planning the vascular connection. Recognizing these issues before or during implantation can reduce the likelihood of anastomotic failure, inadequate graft perfusion, and related recipient complications.