Mouse Fixation Device
Mouse Fixation Device - Related Videos
06:57
Instillation and Fixation Methods Useful in Mouse Lung Cancer Research
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Cited by 48 •
2015
The goal of this paper is to describe simple methods that will greatly aid in the setup and analysis of mouse lungs with lung cancer or other pathologies. We present 3 protocols to simply and reliably carry out lung instillations, fixation, and lung volume measurements.
05:58
Mouse Electroacupuncture Fixation Device Fabrication for Electroacupuncture Pretreatment in Diabetic Cardiomyopathy Mouse Model
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2025
Here, we present a protocol to establish a mouse model of diabetic cardiomyopathy and a mouse electroacupuncture fixation device for the use of electroacupuncture in mice, which can fix the mice more gently during treatment.
05:49
A Simple Device to Rapidly Prepare Whole Mounts of the Mouse Intestine
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Cited by 10 •
2015
The use of a simple device to cut and ‘roll’ mouse intestines to rapidly prepare whole mount preparations is described.
04:32
Whole Mount Preparation of Mouse Intestine: Using a Simple Gut-incising Device to Prepare Whole Mount
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2023
In this video, we demonstrate whole mount preparation of the mouse intestine using a simple gut-incising device. The resulting mounts are of superior and uniform quality and can be used for histological analyses.
02:34
Mouse Headpost Implantation: A Method for Head Fixation in Rodents
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2023
This video shows a headpost implantation surgery in murine model. The headpost is used not only to head-fix and therefore restrain the mouse during experimentation, but also to securely attach a head device in freely moving animals.
FAQs
A shaped body chamber supports the mouse’s position, while adjustable restraints help limit movement without relying on a fixed body shape. Together, these features give the operator more consistent control over the animal and maintain access to the anatomical region required for a procedure. This combination can improve precision when performing injections, sampling, or other biomedical interventions.
Consistent positioning helps keep the intended anatomical region accessible across repeated procedures. It can also reduce differences caused by changes in orientation or movement, making measurements and interventions more comparable. In medical and preclinical research, this standardization supports controlled experimental conditions and may improve the reproducibility of observations collected from different animals or study sessions.
Ventilation features are relevant when the device design and procedure require attention to airflow around the restrained animal. The overview identifies ventilation as an appropriate design consideration rather than a universal requirement for every use. Its inclusion can support a device configuration suited to procedures in which positioning must be maintained while ventilation is also considered.
The main design variables described are the shape of the body chamber, the adjustability of restraints, access to specific anatomical regions, and, when appropriate, ventilation. These features influence how consistently the mouse can be positioned and how easily an operator can perform the planned intervention. Their practical value depends on matching the device configuration to the procedure.
A basic workflow is to select a device configuration suited to the planned intervention, position the mouse within the shaped chamber, adjust the restraints to limit movement, and confirm access to the target anatomical region. The operator can then carry out the injection, blood collection, imaging, dosing, or other intervention under more standardized positioning conditions.
Mouse fixation devices support procedures that require precision and controlled access, including injections, blood collection, imaging, and dosing. Their value extends across medical and preclinical studies because standardized positioning can reduce procedural variability. More consistent handling may help investigators obtain measurements and observations that are easier to compare across animals and experimental conditions.