Epoxy Glue
Epoxy Glue - Related Videos
08:40
TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application
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Cited by 12 •
2016
We describe the simplest protocol to prepare biodegradable medical glue that has an effective hemostatic ability. TAPE is a water-immiscible supramolecular aggregate prepared by mixing of tannic acid, a ubiquitous compound found in plants, and poly(ethylene) glycol, yielding a 2.5 times greater water-resistant adhesion compared with commercial fibrin glue.
06:15
A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
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Cited by 8 •
2015
This protocol aims to alleviate the limitation of poor cell engraftment for stem cell treatment of myocardial infarctions through the use of a hydrogel system and a fibrin-based glue. With this approach, cell-to-tissue contact post-infarction can be maintained, increasing the therapeutic potential of beneficial agents at the site of injury.
10:10
Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags
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2019
This protocol describes light-triggered nuclear translocation of guests in living cells using caged molecular glue tags. This method is promising for site-selective nuclear-targeting drug delivery.
08:05
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
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Cited by 1 •
2022
Here, we present a protocol to treat the great saphenous vein (GSV) and the small saphenous vein (SSV) affected by severe pathological reflux, using an original sclerosing and embolizing cyanoacrylate-based glue composed of N-butyl cyanoacrylate and methacryloxy sulfolane (NBCA+MS).
15:19
Dissecting and Recording from The C. Elegans Neuromuscular Junction
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Cited by 15 •
2009
Application of electrophysiology to accessible synapses provides a quantifiable measure of synaptic activity, useful in analyzing synaptic mutants. This article describes a dissection method used to expose the neuromuscular junctions (NMJ) of Caenorhabditis elegans (C. elegans) and briefly discusses some of the uses to which this preparation can be applied.
FAQs
Mixing the resin with its curing agent starts a chemical crosslinking reaction. During this process, reactive components connect into an interconnected polymer structure, changing the material from a liquid mixture into a rigid solid. This network accounts for the bond’s mechanical stability and helps explain why the cured adhesive can resist moisture and chemicals.
Formulation and curing conditions strongly affect how quickly the adhesive hardens and how strong the final bond becomes. The resin-to-curing-agent system determines the available chemical reaction, while the surrounding conditions influence the progression of crosslinking. Consequently, identical components may produce different curing behavior or bond performance when the formulation or conditions change.
Resistance to moisture and chemicals helps the cured polymer maintain a stable bond when an experimental device encounters those environmental challenges. This durability is especially relevant to neuroscience hardware, where secure construction can support consistent positioning or insulation of nonbiological components. However, resistance alone does not establish suitability for direct contact with biological samples.
A supported workflow begins by selecting a formulation compatible with the intended materials and use, combining the resin with its curing agent, and positioning the mixture where bonding or insulation is needed. The assembly must then remain under appropriate curing conditions until the liquid converts to a rigid polymer. Final material compatibility should also be evaluated.
In neuroscience research, the adhesive can secure nonbiological components within electrode assemblies, imaging hardware, and microfabricated platforms. Its cured mechanical stability helps preserve the physical arrangement of these parts, while its insulating role can separate or protect selected components. These functions support construction of experimental devices without making the adhesive itself a biological measurement.
Researchers should assess material compatibility before using an epoxy-bonded component in contact with biological samples. A formulation that performs well mechanically may not be appropriate for every biological interface, so the intended contact and surrounding materials require separate consideration. This evaluation helps distinguish reliable device construction from suitability for exposure to experimental biological material.