Protein Folding

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.

...

In a newly synthesized peptide, interactions between its constituent amino acids guide its folding into a stable three-dimensional structure called the native conformation, often its functional form.

First, the linear polypeptide chain folds into alpha-helices and beta-sheets through hydrogen bonding between amino acid residues.

Hy...