Tissue-Specific Transcription Factors in Gene Control

Tissue-specific transcription factors help control which genes turn on in different mammal cells. These proteins bind to promoter sequences and can direct a gene to be expressed in one tissue but not another. This selective control helps cells carry out very different jobs in the body.

A clear ex...

In eukaryotic cells, transcription initiation by RNA polymerase II requires at least six different general transcription factors — TFIIA, IIB  , IID, IIE, IIF, and IIH.

These proteins bind to gene promoter regions along with RNA polymerase and regulate the gene expression. 

TFIID is a multiprotein complex containing a TATA-binding ...