Protein Docking in Cell Signaling

Protein docking helps cells build signaling complexes that pass messages inside the cell. These multiprotein complexes form through protein-protein interactions at the cytoplasmic side of transmembrane receptors. They can also include enzymatic and non-enzymatic proteins linked to the receptor. Together, they help activate a...

Signaling complexes are protein clusters assembled on a receptor's intracellular docking sites. This assembly aids signal transduction by grouping molecules into a single location.

Signaling complexes can be assembled in different ways. For example, some signals induce phosphorylation of either a receptor or phosphoinositides in the plasm...