Cross-Talk in Cell Signaling Pathways

Cell signaling pathways often cross-talk with one another. This means one pathway can influence another instead of acting alone. Cells use these linked pathways to combine signals from the environment and respond in a controlled way.

One common pattern is convergence. In convergence, two separate...

Signaling molecules and receptors work in different combinations to regulate the diverse cellular functions.

Signals from different receptors, each stimulated by their ligand, can converge to activate a common downstream effector — a protein that triggers a specific cellular response.

Individual signals from G-protein coupled recep...