Replisome Components in DNA Copying

The replisome is the protein machine that copies DNA during cell division. It works at the replication fork, where the double helix opens so new strands can be made.

DNA polymerase is the core enzyme in the replisome. It adds nucleotides to the growing DNA strand. In bacteria, two DNA polymerases...

DNA replication is carried out by a highly coordinated multi-protein assembly known as the DNA replication machinery or the replisome, which increases the efficiency of DNA replication.

The core components of the machinery are helicase, single-strand DNA binding proteins, DNA primase, sliding clamps, a clamp loader, and multiple DNA polym...