Homologous Recombination in DNA Repair

Homologous recombination is a DNA repair process that uses a matching DNA sequence as a template. It helps cells fix breaks in DNA and keep genetic information accurate.

The process begins when a broken DNA strand finds a similar, or homologous, piece of DNA. That matching sequence guides repair ...

An essential requirement of DNA replication is to maintain the integrity of the genetic material. For this reason double-strand breaks are preferentially repaired by homologous recombination and it is typically carried out after DNA synthesis when the two daughter DNA molecules are in proximity, and one can serve as a template for repair of the ...