RNA Polymerase Steps in Prokaryotes

Transcription in prokaryotes follows a set of RNA polymerase steps that turn genetic information into RNA. The process has three main stages: initiation, elongation, and termination. Each stage uses specific molecular interactions to control when and how RNA is made.

During initiation in bacteria...

Transcription includes initiation, elongation, and termination.

The bacterial core RNA polymerase binds a sigma factor, forming a holoenzyme for initiation.

This sigma factor interacts with promoter regions, like the -35 and -10 sequences, positioning the RNA polymerase near the transcription start site.

After binding, the holo...