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ABO blood grouping divides human blood into four types based on the presence or absence of two specific antigens, antigen A and antigen B, on the red blood cell surface. These antigens are encoded by three alleles.
The allele immunoglobulin A, or simply allele A, codes for antigen A on the surface of the red blood cell. Similarly, allele B codes for antigen B.
The third allele - recorded as lowercase i and referred to as allele O - does not code for the antigen, meaning the red blood cells have neither antigen A nor antigen B.
Since the antigen's presence dictates the blood type, the alleles A and B are dominant over allele O, which does not produce any antigens.
Humans are diploid organisms, and therefore they receive two copies of the alleles, one from each parent. A person with two copies of allele A or one copy of A and the recessive allele O has type A blood. Similarly, a person with two copies of allele B or one copy of B and the recessive allele O has type-B blood.
Having one copy of allele A and one of allele B results in type AB blood, an example of codominance, where both antigens are expressed on the red blood cell surface. Conversely, a person with both copies of the r
Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper…
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