Trial ends in

### 12.1: What is an Experiment? TABLE OFCONTENTS X ## Chapter 1: Understanding Statistics 301.1: Introduction to Statistics301.2: How Data are Classified: Categorical Data301.3: How Data are Classified: Numerical Data301.4: Nominal Level of Measurement301.5: Ordinal Level of Measurement301.6: Interval Level of Measurement301.7: Ratio Level of Measurement301.8: Data Collection by Observations301.9: Data Collection by Experiments301.10: Data Collection by Survey301.11: Random Sampling Method301.12: Systematic Sampling Method301.13: Convenience Sampling Method301.14: Stratified Sampling Method301.15: Cluster Sampling Method ## Chapter 2: Summarizing and Visualizing Data 302.1: Review and Preview302.2: What is a Frequency Distribution302.3: Construction of Frequency Distribution302.4: Relative Frequency Distribution302.5: Percentage Frequency Distribution302.6: Cumulative Frequency Distribution302.7: Ogive Graph302.8: Histogram302.9: Relative Frequency Histogram302.10: Scatter Plot302.11: Time-Series Graph302.12: Bar Graph302.13: Multiple Bar Graph302.14: Pareto Chart302.15: Pie Chart ## Chapter 3: Measure of Central Tendency 303.1: What is Central Tendency?303.2: Arithmetic Mean303.3: Geometric Mean303.4: Harmonic Mean303.5: Trimmed Mean303.6: Weighted Mean303.7: Root Mean Square303.8: Mean From a Frequency Distribution303.9: What is a Mode?303.10: Median303.11: Midrange303.12: Skewness303.13: Types of Skewness ## Chapter 4: Measures of Variation 304.1: What is Variation?304.2: Range304.3: Standard Deviation304.4: Standard Error of the Mean304.5: Calculating Standard Deviation304.6: Variance304.7: Coefficient of Variation304.8: Range Rule of Thumb to Interpret Standard Deviation304.9: Empirical Method to Interpret Standard Deviation304.10: Chebyshev's Theorem to Interpret Standard Deviation304.11: Mean Absolute Deviation ## Chapter 5: Measures of Relative Standing 305.1: Review and Preview305.2: Introduction to z Scores305.3: z Scores and Unusual Values305.4: Percentile305.5: Quartile305.6: 5-Number Summary305.7: Boxplot305.8: What Are Outliers?305.9: Modified Boxplots ## Chapter 6: Probability Distributions 306.1: Probability in Statistics306.2: Random Variables306.3: Probability Distributions306.4: Probability Histograms306.5: Unusual Results306.6: Expected Value306.7: Binomial Probability Distribution306.8: Poisson Probability Distribution306.9: Uniform Distribution306.10: Normal Distribution306.11: z Scores and Area Under the Curve306.12: Applications of Normal Distribution306.13: Sampling Distribution306.14: Central Limit Theorem ## Chapter 7: Estimates 307.1: What are Estimates?307.2: Sample Proportion and Population Proportion307.3: Confidence Intervals307.4: Confidence Coefficient307.5: Interpretation of Confidence Intervals307.6: Critical Values307.7: Margin of Error307.8: Sample Size Calculation307.9: Estimating Population Mean with Known Standard Deviation307.10: Estimating Population Mean with Unknown Standard Deviation307.11: Confidence Interval for Estimating Population Mean ## Chapter 8: Distributions 308.1: Distributions to Estimate Population Parameter308.2: Degrees of Freedom308.3: Student t Distribution308.4: Choosing Between z and t Distribution308.5: Chi-square Distribution308.6: Finding Critical Values for Chi-Square308.7: Estimating Population Standard Deviation308.8: Goodness-of-Fit Test308.9: Expected Frequencies in Goodness-of-Fit Tests308.10: Contingency Table308.11: Introduction to Test of Independence308.12: Hypothesis Test for Test of Independence308.13: Determination of Expected Frequency308.14: Test for Homogeneity308.15: F Distribution ## Chapter 9: Hypothesis Testing 309.1: What is a Hypothesis?309.2: Null and Alternative Hypotheses309.3: Critical Region, Critical Values and Significance Level309.4: P-value309.5: Types of Hypothesis Testing309.6: Decision Making: P-value Method309.7: Decision Making: Traditional Method309.8: Hypothesis: Accept or Fail to Reject?309.9: Errors In Hypothesis Tests309.10: Testing a Claim about Population Proportion309.11: Testing a Claim about Mean: Known Population SD309.12: Testing a Claim about Mean: Unknown Population SD309.13: Testing a Claim about Standard Deviation ## Chapter 10: Analysis of Variance 3010.1: What is an ANOVA?3010.2: One-Way ANOVA3010.3: One-Way ANOVA: Equal Sample Sizes3010.4: One-Way ANOVA: Unequal Sample Sizes3010.5: Multiple Comparison Tests3010.6: Bonferroni Test3010.7: Two-Way ANOVA ## Chapter 11: Correlation and Regression 3011.1: Correlation3011.2: Coefficient of Correlation3011.3: Calculating and Interpreting the Linear Correlation Coefficient3011.4: Regression Analysis3011.5: Outliers and Influential Points3011.6: Residuals and Least-Squares Property3011.7: Residual Plots3011.8: Variation3011.9: Prediction Intervals3011.10: Multiple Regression ## Chapter 12: Statistics in Practice 3012.1: What is an Experiment?3012.2: Study Design in Statistics3012.3: Observational Studies3012.4: Experimental Designs3012.5: Randomized Experiments3012.6: Crossover Experiments3012.7: Controls in Experiments3012.8: Bias3012.9: Blinding3012.10: Clinical Trials Full Table of Contents

JoVE Core
Statistics

A subscription to JoVE is required to view this content.
You will only be able to see the first 20 seconds.

Education
What is an Experiment?

### 12.1: What is an Experiment?

An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The different values of the explanatory variable are called treatments. An experimental unit is a single object or individual to be measured.

You want to investigate the effectiveness of vitamin E in preventing disease. You recruit a group of subjects and ask them if they regularly take vitamin E. You notice that the subjects who take vitamin E exhibit better health on average than those who do not. Does this prove that vitamin E is effective in disease prevention? It does not. There are many differences between the two groups compared in addition to vitamin E consumption. People who take vitamin E regularly often take other steps to improve their health: exercise, diet, other vitamin supplements, and choosing not to smoke. Any one of these factors could be influencing health. As described, this study does not prove that vitamin E is the key to disease prevention.

Additional variables that can cloud a study are called lurking variables. In order to prove that the explanatory variable is causing a change in the response variable, it is necessary to isolate the explanatory variable. The researcher must design her experiment in such a way that there is only one difference between the groups being compared: the planned treatments. This is accomplished by the random assignment of experimental units to treatment groups. When subjects are assigned treatments randomly, all of the potential lurking variables are spread equally among the groups. At this point, the only difference between groups is the one imposed by the researcher. Therefore, different outcomes measured in the response variable must be a direct result of the different treatments. In this way, an experiment can prove a cause-and-effect connection between the explanatory and response variables.

This text is adapted from Openstax, Introductory Statistics, Section 1.4 Experimental Design and Ethics

X