Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex

Abstract

Source: Lioumis, P. et al. Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex. J. Vis. Exp. (2018)

This video demonstrates a protocol for combining transcranial magnetic stimulation and electroencephalography to assess cortical excitability and the balance between excitation and inhibition in the dorsolateral prefrontal cortex.

Protocol

All procedures involving human participants have been performed in compliance with the institutional, national, and international guidelines for human welfare and have been reviewed by the local institutional review board.

1. Hot spot and motor threshold:
   1. Instruct the participant to be at rest- comfortable and with relaxed hands, legs and spinal column.
   2. Find the hot spot. Target the motor knob at the initial landmark of cortical representation of the abductor pollicis brevis muscle (APB) in motor cortex (M1) and move the coil until there is corresponding APB movement. Use transcranial magnetic stimulation (TMS) intensities evoking mo....

Materials

List of materials used in this article

Name	Company	Catalog Number	Comments
BISTIM'2 Package Option 1	Magstim	3234-00	TMS paired pulse stimulator
Magstim 200'2 Unit (2 items)	Magstim	3010-00	TMS stimulators
UI controller	Magstim	3020-00	TMS controller
BISTIM'2 UI controller	Magstim	3021-00	TMS controller
BISTIM connecting module	Magstim	3330-00	TMS connecting module
D70 Alpha Coil - P/N 4150-00 (Alpha 70mm double coil)	Magstim	4150-00	TMS coil
Brainsight	Rogue-Resolutions	Brainsight 2	Neuronavigator
Model 2024F	Intronix	2024F	Electromyograph
Neuroscan SynAmps RT 64 channel System	Compumedics Neuroscan	9032-0010-01	Electroencephalograph
Quick-Cap electrode system 64	Compumedics Neuroscan	96050255	EEG Cap