Surgical Implantation of Temperature Telemetric Monitoring System in Mouse Model: A Surgical Procedure to Implant Temperature Telemetric Device to Measure Mouse Core Body Temperature

Abstract

Source: King, M. A. et al.  A Preclinical Model of Exertional Heat Stroke in Mice. J. Vis. Exp. (2021)

In this video, we describe a surgical procedure to implant a temperature telemetric device  in a mouse model to continuously measure its core body temperature.

Protocol

All procedures involving animal models have been reviewed by the local institutional animal care committee and the JoVE veterinary review board

1. Surgical Implantation of the Telemetric Temperature Monitoring System

1. Upon arrival from the vendor, allow the animals to rest in the vivarium for at least 1 week prior to surgery to minimize the stress of transportation.
2. Group house the mice (maximum of 5 per cage under local IACUC guidelines) until the day of surgery for temperature telemetric device implantation. House them in standard 7.25" (W) x 11.75" (L) x 5" (H) cages containing corncob bedding. Maint....

Materials

List of materials used in this article

Name	Company	Catalog Number	Comments
5-0 Ethilon Nylon Suture Black Monofilament	Ethicon
Adhesive Surgical Drape with Povidone 12x18	Jorgensen Labset
DR Instruments Medical Student Comprehensive Anatomy Dissection Kit	DR Instruments
Energizer Power Supply	Starr Life Sciences
G2 Emitter et al.	Starr Life Sciences
Patterson Veterinary Isoflurane	Patterson Veterinary
Platform receiver et al.	Starr Life Sciences
Scientific Environmental Chamber Model 3911	ThermoForma
BK Precision Multi-Range Programmable DC Power Supplies Model 9201	BK Precision