Method Article

Recording Cortical and Subcortical Neuronal Activity Using Electrode Systems

July 8th, 2025

In This Article

Abstract

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Source: Trenado, C., et al. Combined Invasive Subcortical and Non-invasive Surface Neurophysiological Recordings for the Assessment of Cognitive and Emotional Functions in Humans. J. Vis. Exp. (2016).

This video demonstrates the process of recording cortical and subcortical neuronal activity using electroencephalography (EEG) and deep brain stimulation (DBS) electrodes during an attention-based visual stimulation test.

Protocol

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All procedures involving human participants have been performed in compliance with the institutional, national, and international guidelines for human welfare and have been reviewed by the local institutional review board.

1. Experimental Paradigm Design and Patient's Consent

NOTE: Design an experimental paradigm or select an existing experimental paradigm to target a cognitive/emotional aspect of interest.

  1. Select patients who will undergo DBS treatment. Ask if the patient meets the study's inclusion criteria. If yes, obtain signed informed consent from the patient an....

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Results

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Arrows task setup; response diagram for cognitive experiment; includes stimuli and trial descriptions.
Figure 1: Sample Experimental Paradigms. (A) (Example 1) Flanker task: target stimulus (arrowhead in the center) is flanked by two adjacent arrows (above and below target) either pointing in the same (compatible) or opposite (incompatible) direction, .......

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Disclosures

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No conflicts of interest declared.

Materials

List of materials used in this article
NameCompanyCatalog NumberComments
BrainAmp AmplifierBrain Products GmbH, Gilching GermanyQuantity: 2
BrainVision Recorder SoftwareBrain Products GmbH, Gilching Germany1 License
BrainVision Analyzer SoftwareBrain Products GmbH, Gilching Germany1 License
Fiber Optic cables and USB connectorsBrain Products GmbH, Gilching GermanyThese come with the above listed equipment
Electrode Input box (64 channels)Brain Products GmbH, Gilching GermanyQuantity: 1
EEG gelNatus IncQuantity: 1
Isopropyl alcoholSchülke & Mayr GmbH, GermanyQuantity: 1
Skin preparation gelWeaver and Co, USAQuantity: 1
MATLABMath-Works, Natick, Massachusetts, USA1 License
FieldTrip toolboxhttp://www.fieldtriptoolbox.org/Open Source
INOMED MER systemINOMED Corp., Emmendingen, GermanyQuantity: 1
Macroelectrodes (model 3387 quadripolar DBS lead)Medtronic Inc., Minneapolis, MN, USAQuantity: 2
Sterile percutaneous extension wires (model 3550-05)Medtronic Inc., Minneapolis, MN, USAQuantity: 2
Twist lock cable (model 3550-03)Medtronic Inc., Minneapolis, MN, USAQuantity: 2
custom made connectors to DIN 428092 touch proof connectorsQuantity: 2
Vercise Lead kit DB -2201Boston ScientificQuantity: 2
Contact extenion kit NM-3138Boston ScientificQuantity: 2
O.R. cabel & extension SC-4100 ABoston ScientificQuantity: 2
connector to touch proofTwente Medical Systems International B.V.Quantity: 2
CT scanner Modell PQ2000 (Postoperative CT scans)Philips Healthcare GmbH HamburgQuantity: 1
Presentation Software (Flanker Task)Neurobehavioral systems Inc.1 License

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Tags

Cortical Neuronal ActivitySubcortical Neuronal ActivityEEG Electrode PlacementDBS Electrode RecordingVisual Stimulation TestFlanker Task PerformanceEEG Recording SoftwareSignal Amplification SystemInternational 10 20 SystemLocal Field Potential

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