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Method Article

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

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DOI:

10.3791/56790

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December 11th, 2017

In This Article

Summary

Valve-sparing aortic root replacement has the advantage of preserving the patient's own aortic valve. The complexity of the reported techniques to date restricts their use to a limited number of cardiac surgeons. This protocol describes step-by-step a standardized technique reproducible by a greater number of cardiac surgeons.

Abstract

Despite the obvious advantages of the preservation of a normal aortic valve during aortic root replacement, the complexity of valve sparing procedures prevents a number of cardiac surgeons from incorporating them into their practice. The aim of this protocol is to describe a simplified and user-friendly technique of an aortic valve-sparing root replacement (VSRR) procedure by re-implantation of the aortic valve. Proper selection of patients and limitations of the technique are discussed.

In 54 consecutive patients, normal appearing aortic valves were re-implanted in a commercially available polyester prosthesis with pre-shaped sinuses by a simplified and standardized technique. Placement of the first row of the proximal suture line, choice of the prosthesis size, and adjustment of the height of the commissures of the patient to the fixed height of the sinus portion of the prosthesis were slightly modified from the reference techniques with the aim of increasing its feasibility for use by other cardiac surgeons. Early mortality and morbidity as well as 5-year survival, freedom from aortic valve reoperation, and freedom from recurrent moderate regurgitation were collected in all patients.

Thirty-day mortality, re-sternotomy for bleeding, re-sternotomy for mediastinitis, and the incidence of stroke were very low, 1.8% for each (1 of 54). No patient required permanent pace-maker implantation. At 5 years, survival, freedom from aortic valve reoperation, and freedom from recurrent moderate regurgitation were 97.5%, 95.2%, and 91.6%, respectively.

Mid-term results of our standardized technique of re-implantation of the aortic valve for valve-sparing aortic root replacement are very good and compare with more complex techniques reported by experienced surgeons. By following the present protocol of the standardized re-implantation technique, a greater number of cardiac surgeons can perform this procedure with comparable good results.

Introduction

During the past twenty years, the surgical treatment of aortic root aneurysm with normal or near-normal aortic cusps has evolved thanks to a series of surgical procedures aiming at preservation of the native aortic valve1,2,3,4,5. Valve-sparing aortic root replacement is basically accomplished either by re-implantation of the aortic valve inside a synthetic graft1,3,4,6 or by a re....

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Protocol

The protocol follows the institutional guidelines of the human research ethics committee.

1. Pre-selection of the Patient

  1. Identify patients with dilation of the sinuses of Valsalva not exceeding 60 mm using the pre-operative computer tomography (CT) scan.
  2. Next, select among these patients a subgroup with normal or near-normal appearing aortic valve cusps on their pre-operative echocardiography.
  3. Inform the staff of the possibility of a valve sparing aortic root replacement procedure.
  4. Make the final decision intra-operatively after inspection of the aortic valve. Verify the absence of calcifications o....

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Results

Statistical Analysis:

Continuous variables are presented as mean ± standard deviation and categorical variables as percentages. Kaplan-Meier curves are calculated for survival, freedom from aortic valve reoperation, and freedom from recurrent moderate regurgitation using a commercially available software package.

Patient Population:

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Discussion

In patients presenting with aortic root aneurysm with normal or near-normal aortic cusps, valve-sparing aortic root replacement is a more physiological and hence attractive alternative to composite graft replacement of the aorta and the aortic valve with mechanical or tissue valve. In this protocol, we describe a simplified technique of valve-sparing aortic root replacement by re-implantation of the aortic valve. In contrast to the majority of the previously reported techniques3,

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Disclosures

The authors have nothing to disclose.

Acknowledgements

This work was supported by a grant (N° 32117) of the Swiss Cardiovascular Foundation to RT.

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Materials

List of materials used in this article
NameCompanyCatalog NumberComments
Heart surgery infrastructure:
Heart Lung MachineStockertSIII
EOPA 24Fr. arterial cannulaMedtronic77624
Atrial caval venous cannula 34/48Fr.Medtronic93448
LV vent catheter 17Fr.EdwardsE061
Antegrade 9Fr. cardioplegia cannulaEdwardsAR012V
Retrograde 14Fr. cardioplegia cannula EdwardsNPC014 
Coronary artery ostial cannula 90°Medtronic30155
Coronary artery ostial cannula 45°Medtronic30255
NameCompanyCatalog NumberComments
Pre-shaped sinus graft
Cardioroot 28 mmMaquetHEWROOT0028
Cardioroot 30 mmMaquetHEWROOT0030
Cardioroot 32 mmMaquetHEWROOT0032
NameCompanyCatalog NumberComments
ElectrocauteryCovidienForce FX
NameCompanyCatalog NumberComments
Sutures:
Polypropylene 4/0Ethicon8871H
Polypropylene 5/0Ethicon8870H
Polypropylene 6/0EthiconEH7400H
Braided polyesther 2/0 ligature with polybutylate coating EthiconX305H
NameCompanyCatalog NumberComments
Micro knife Sharpoint TYCO Healthcare PTY 78-6900
NameCompanyCatalog NumberComments
Drugs:
MidazolamRoche PharmaN05CD08
RocuroniumMSD Merck Sharp & Dohme M03AC09
PropofolFresenius KabiN01AX10
FentanilActavisN01AH01
HeparinBraunB01AB01
ProtaminMEDA PharmaceuticalV03AB14
NameCompanyCatalog NumberComments
Instruments:
Cooley vascular aortic clampDelacroix-ChevalierDC40810-16
Dissection forceps CarpentierDelacroix-ChevalierDC13110-28 
Scissors MetzenbaumDelacroix-ChevalierB351751
Needle holder RyderDelacroix-ChevalierDC51130-20 
Dissection forceps DeBakeyDelacroix-ChevalierDC12000-21 
Micro needle holder JacobsonDelacroix-ChevalierDC50002-21 
Micro scisors JacobsonDelacroix-ChevalierDC20057-21 
Lung retractorDelacroix-ChevalierB803990
Allis clampDelacroix-ChevalierDC45907-25 
O’Shaugnessy DissectorDelacroix-ChevalierB60650
18 blade knifeDelacroix-ChevalierB130180
Leriche haemostatic clampDelacroix-ChevalierB86555
NameCompanyCatalog NumberComments
Data analysis
Kaplan Meier curvesGraphPadPrism 7

References

  1. David, T. E., Feindel, C. M., Bos, J. Repair of the aortic valve in patients with aortic insufficiency and aortic root aneurysm. J Thorac Cardiovasc Surg. 109 (2), 345-352 (1995).
  2. Yacoub, M. H., Gehle, P., Chandrasekaran, V., Birks, E. J., Child, A., Radley-Smith, R.

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Tags

Prosthesis Implantation TechniqueProximal Suture PlacementCoronary Ostia ReconnectionMembranous Septum ProtectionSurgical Procedure StandardizationCardiac Surgery TechniquePostoperative Outcomes Analysis