CAUTION: Please review all relevant material safety data sheets (MSDS) before use. Follow all appropriate safety practices when using the microwave reactor including reviewing the microwave reactor protocols and the use of personal protective equipment (safety glasses, gloves, lab coat, full-length pants, closed-toe shoes). This procedure is designed to work using an aryl hydrazine and either 3-aminocrotononitrile or an α-cyanoketone. The appropriate microwave vial and stir bar should be used according to the scale of the reaction as specified by the manufacturer.
1. Preparation of reaction mixture
NOTE: The f....