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Cloud computing has become essential for modern data services, offering flexibility, scalability, and efficiency. However, with this widespread adoption comes increased exposure to cyber threats, especially those targeting data confidentiality and integrity. Traditional encryption algorithms such as AES-256 and RSA, though widely used, face growing limitations. These methods require heavy computational resources and are vulnerable to evolving technologies like quantum computing1. This creates an urgent need for novel encryption systems that are lightweight, scalable, and future-proof.
DNA-based cryptography has emerged as a promising alternative due to its inherent complexity, randomness, and potential for parallel computation2. However, the theoretical appeal of these methods often clashes with their practical implementation. Most existing DNA-based schemes have struggled with real-world applicability as they are often hardware-dependent, require specialized laboratory equipment, or lack the performance and scalability needed for dynamic cloud environments3. These limitations have created a significant gap between the theoretical promise of bio-inspired security and its practical applicability.
To address this, we present Variational DNA-Based Data Security (VDNABDS)-a software-based encryption framework that transforms user-specific inputs into dynamic DNA-like keys using SHA-256 and XOR operations. The method enables key generation in under 5 ms and encrypts large data volumes in just 4 s, significantly outperforming earlier models like CSDES and ZMCACM4. VDNABDS supports over 1 x 1038 unique key combinations, providing strong protection against brute-force and quantum attacks.
While many researchers have explored solutions to cloud security, they often focus on specific, isolated problems. For instance, Wang et al.5 proposed a secure authentication model for cloud computing, but it lacks content-level encryption capabilities. Similarly, Ahmed et al.6developed DNACDS for IoE environments, yet the scheme suffers from limited scalability in real-time testing. Other efforts combine Blowfish with blockchain7or apply DNA for access control8, but they often fall short in performance or adaptability. VDNABDS fills these gaps with its fast, hardware-independent, and session-specific encryption strategy, which is validated using CloudSim with a large dataset and concurrent users.
In summary, this work provides the following key contributions to the field of cloud security and DNA-based cryptography. We introduce VDNABDS, a novel, software-only cryptographic framework that transforms user-specific information into dynamic DNA-like encryption keys. We demonstrate exceptional performance and scalability, with VDNABDS achieving key generation in just 5 ms and encrypting a 3GB dataset in 4.1 s, outperforming existing models like ZMCACM and AES-256. We validate the protocol's post-quantum security by demonstrating a 1024-bit DNA-derived key and non-algebraic transformations, which provide a security level well beyond the NIST threshold and resist both Shor's and Grover's algorithms9. We propose a dual-layer key protection scheme combining Elliptic Curve Cryptography (ECC) and RSA-OAEP to securely wrap the DNA key, enhancing its resistance against brute-force and replay attacks10.