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TOPICAL COLLECTIONS

Recent Advances in Basic and Applied Cyanobacterial Research

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Harinder Singh

Harinder Singh

SVKM’s NMIMS Deemed to be University, Sunandan Divatia School of Science, Department of Biological Sciences

Dr. Harinder Singh is a research faculty at SVKM’s NMIMS, Sunandan Divatia School of Science and is currently working in the area of stress biology, enzyme engineering, and microbiome. He has previously worked in the area of stress biology using cyanobacterial and bacterial model systems. These studies were mainly targeted to explore and understand the physiological and molecular mechanisms underlying different stress responses such as oxidative stress, desiccation and radiation stress. The work has been extended to cold shock response, which is a currently active project of his group. Dr. Singh has also worked on enzyme biotransformation, where novel enzymes were explored for asymmetric chiral synthesis. Enzyme engineering approach was also utilized to meet these objectives. On similar lines, he is currently working on using in silico bioprospecting and enzyme engineering approach to obtain better enzyme candidates. Another active study of his group is in the area of microbiome, where metagenomics approach is being used to explore the human microbiome and its correlations with health conditions.

Collection Overview

Cyanobacteria represent one of the most ancient and ecologically significant groups of photosynthetic microorganisms, playing pivotal roles in global carbon and nitrogen cycles, primary productivity, and ecosystem stability. In recent years, they have also emerged as versatile platforms for applications spanning biotechnology, bioenergy, agriculture, environmental remediation, and synthetic biology. Rapid advances in genomics, metabolic engineering, systems biology, and ecological modeling have substantially expanded our understanding of cyanobacterial physiology, diversity, and functional potential, underscoring their relevance in addressing pressing environmental and industrial challenges.


Despite this progress, the field continues to face several critical challenges. These include limitations in genetic tractability across diverse strains, incomplete understanding of regulatory networks under dynamic environmental conditions, scalability issues in industrial applications, and concerns related to harmful algal blooms and toxin production. Furthermore, translating laboratory-scale discoveries into real-world solutions remains a significant bottleneck, compounded by gaps in interdisciplinary integration and standardization of experimental approaches.


This Collection aims to provide a comprehensive platform that captures the breadth of contemporary cyanobacterial research. It seeks to bring together methodological advancements, original research articles, and reviews that collectively reflect both foundational discoveries and translational innovations.


By consolidating cutting-edge discoveries, methods and advancements, this collection will serve as a valuable resource for researchers and industry stakeholders. It will not only enhance conceptual understanding and technical capabilities but also accelerate the development of sustainable, cyanobacteria-based solutions to global challenges.

Articles

Isolation and Characterization of Intact Phycobilisome in Cyanobacteria
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Isolation and Characterization of Intact Phycobilisome in Cyanobacteria

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Cited by 4

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2021

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