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TOPICAL COLLECTIONS

Animal Models for the Study of Cardiovascular Diseases

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Hung-Fat Tse

Hung-Fat Tse

The University of Hong Kong, Department of Medicine

Professor Hung-Fat Tse is the Chair Professor of Cardiovascular Medicine and William MW Mong Endowed Professor in Cardiology, Chief of the Cardiology Division, Department of Medicine, Queen Mary Hospital. He received his medical degree from the University of Hong Kong, Hong Kong and he completed his postgraduate training in Internal Medicine and Cardiology in the Department of Medicine, Queen Mary Hospital, University of Hong Kong, and his cardiac-electrophysiology training fellowship at the University of Michigan, USA.\Professor Tse is an international expert in cardiac pacing and electrophysiology, and cardiovascular regenerative medicine. He has significantly contributed to the understanding of the mechanisms as well as development of novel therapies for treatment of heart rhythm disorder. In addition, Professor Tse is at the forefront of applying stem cells in cardiovascular regenerative medicine. His research center and basic laboratory together with the Sun Chieh Yeh Cardiovascular Research and Training Laboratory (for large animal research) are dedicated to the training and development of novel device and biological therapies for cardiovascular diseases. Prof. Tse has published over 520 original scientific reports in international scientific journals, including New England Journal of Medicine, Nature Medicine, Lancet, Cell Stem Cell, Circulation, Blood, Journal of American College of Cardiology, Archives of Internal Medicine, American Journal of Medicine, European Heart Journal and Stem Cell.

Collection Overview

Cardiovascular diseases are the first leading cause of death and morbidity worldwide, including hypertension, heart failure, acute myocardial infarction and peripheral vascular disease. Animal models of cardiovascular diseases can provide important information to understand the cardiovascular risk factors and disease pathogenesis. They are also very useful for translational medicine in discovery and evaluation of drugs, genes, devices, biomaterials or stem cells treatment of cardiovascular diseases. The aim of this collection is to address some improved and specialized animal models (mouse, rat, pig, primate) for the study of cardiovascular diseases. Submissions of original research papers and videos, focused on different aspects of novel experimental models, including description and characterization of novel methodologies, diagnostic techniques, medical and surgical treatments applied in small or large animals are welcomed.

Articles

Precision Ultrasound-guided Stem Cell Delivery for Vascular Repair in Aortic Diseases
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Precision Ultrasound-guided Stem Cell Delivery for Vascular Repair in Aortic Diseases

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Cited by 3

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2025

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Abstracts

Using Radiotelemetry to Characterize Mouse Models with Preeclampsia-like Features

Jenny Sones*1

1Louisiana State University School of Veterinary Medicines