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Methods in Behavioral Neuroendocrinology

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Sarah Ferri

Sarah Ferri

University of Iowa

Dr. Sarah Ferri received her PhD from the University of Pennsylvania, focusing on behavioral neuroendocrinology. She is currently a Postdoctoral Scholar in the Department of Neuroscience and Pharmacology at the University of Iowa. Dr. Ferri uses mouse models to study the neurobiological underpinnings of neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. Specifically, she is interested in sex differences in prevalence, severity, and progression of sex-biased conditions. Determining the mechanisms underlying vulnerability and resilience will facilitate the goal of early detection, effective treatment, and prevention. She uses behavioral, pharmacological, genetic, molecular, cellular, and imaging techniques.  

Collection Overview

The study of behavioral neuroendocrinology encompasses a number of evolutionarily important behaviors regulated by a variety of hormones that act on receptors throughout the brain via diverse mechanisms to modulate development and behavior.  Hormone-brain interactions regulate a wide range of biological processes such as fetal development, puberty, stress, arousal, appetite, and gene expression. The numerous hormone types, including estrogens, androgens, gonadotropins, leptin, corticosterone, oxytocin, vasopressin, insulin, glucagon, epinephrine, norepinephrine, somatostatin, and thyroid hormone, in conjunction with several classes of receptors and brain area targets make this field of study both complex and important. Hormones also play an essential role in sex-specific behaviors and responses, and evaluation of hormonal status and neuroendocrine interactions are important in the consideration of sex as a biological variable, which is a significant issue that is gaining acknowledgment. In addition, hormones regulate immune response and the HPA axis, and hormonal dysregulation is implicated in mood, metabolic, and sexual disorders, making neuroendocrine pathways important drug targets. This collection brings together an array of behavioral and procedural methods that aid in our understanding of highly conserved behaviors and developmental processes that are critical for survival and reproductive success and dependent on hormone mechanisms in the brain. Topics may include parental behavior, social affiliative behavior, aggression, and reproductive behavior.

Articles

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
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Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

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Cited by 6

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2020

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