Biological Characterization of Nanomaterials

TOPICAL COLLECTIONS

Guest Editor

Ebrahim Mostafavi

Stanford University School of Medicine, Stanford Cardiovascular Institute

Dr. Ebrahim Mostafavi, PhD is currently at the Stanford Cardiovascular Institute, Stanford School of Medicine. His research interests revolve around the use of cardiac iPS cells to design and develop in vitro models (organoids, 3D bioprinted constructs, vascular grafts) for cardiovascular disease modeling and drug screening, as well as CRISPR/Cas gene-editing for cardiovascular diseases. Dr. Mostafavi received his PhD in Chemical Engineering (with a focus on Biomedical Engineering and Regenerative Medicine) from Northeastern University, Boston, MA. During his doctoral training, he received several prestigious awards. He has also received training at Harvard Medical School/Brigham and Women's Hospital on engineering and development of (nano)biomaterials and 3D scaffolds (hydrogels, 3D bioprinted constructs, and nanoporous scaffolds) to create biologically complex tissues and organs for tissue engineering, regenerative medicine, and translational applications. His scholarly work consists of > 70 publications with an H-index of 22 (i10-index= 35) on Google Scholar Profile. He currently serves as the Associate Editor-in-Chief of the International Journal of Nanomedicine (IF=6.4, Q1) at Dove Medical Press/T&F, and Associate Editor of Frontiers in Nanotechnology-Biomedical Nanotechnology. He is also an Editorial Board Member of several biomedical and materials engineering journals, including, Nature Scientific Reports, Springer Nature Journal of Nanostructure in Chemistry, MDPI Cells, MDPI Journal of Functional Biomaterials, BMC Biotechnology, BMC Biomedical Engineering, Current Medicinal Chemistry, etc. He also contributed to more than 15 book chapters and was selected as the editor of several books.

Collection Overview

Over the past four decades, nanomaterials (including nanoparticles, nanotubes, nanotextured surfaces, self-assembled nanomaterials, etc.) have demonstrated an unprecedented ability to control cell functions important for preventing, diagnosing, and treating various diseases. Medical applications in which nanomaterials have already had a profound impact include increased regeneration of tissues (such as bone, cartilage vascular, nervous system, bladder, skin, etc.), inhibited infection from bacteria, decreased cancerous tumor growth, and most recently, passivation of SARS-CoV-2 which leads to COVID-19. Despite such promising applications of nanomaterials in medicine, there is a lack of standard methods that exist for the in vitro and in vivo assessment of such novel materials. Moreover, one of the most significant concerns of nanomaterials used in biological applications includes their toxicity and wide distribution throughout the body.

This methods collection aims to cover assays used to determine the biological properties of nanomaterials. Overall, this collection will provide a comprehensive reference guide of in vitro and in vivo standard methods that can be used to assess various health applications of nanomaterials, including their potential toxicity.

Articles

7:14

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

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Cited by 4

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2022

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Sougata Ghosh^1,2,3, Tanay Bhagwat³, Rohini Kitture⁴, Sirikanjana Thongmee¹, Thomas J. Webster^3,5,6,7

¹Department of Physics, Faculty of Science, Kasetsart University, ²Department of Microbiology, School of Science, RK. University, ³Department of Chemical Engineering, Northeastern University, ⁴Defence Institute of Advanced Technology Campus, Navyukti Innovations Pvt. Ltd., ⁵Department of Biomedical Engineering, Hebei University of Technology, ⁶Department of Chemistry, Saveetha School of Engineering, Institute of Medical and Technical Science, Saveetha University, ⁷UFPI - Universidade Federal do Piauí

8:55

Fabrication and Characterization of Layer-By-Layer Janus Base Nano-Matrix to Promote Cartilage Regeneration

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Cited by 13

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2022

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Maxwell Landolina*¹, Anne Yau*¹, Yupeng Chen¹

¹Department of Biomedical Engineering, University of Connecticut

8:18

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs

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Cited by 6

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2022

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Mubashar Rehman*¹, Muhammad Ziaullah Khan*¹, Muhammad Tayyab*¹, Asadullah Madni², Qandeel Khalid^1,3

¹Department of Pharmacy, Quaid-i-Azam University, ²Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, ³Nazar College of Pharmacy

Developing and Testing Methylated Nano-Structured Dipeptides that Inhibit Src Kinase Activity <em>In Vitro</em> for Anti-Cancer Applications

Developing and Testing Methylated Nano-Structured Dipeptides that Inhibit Src Kinase Activity In Vitro for Anti-Cancer Applications

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2022

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Alaa F. Nahhas¹, Alrayan F. Nahhas², Thomas J. Webster^3,4,5

¹Biochemistry Department, College of Science, King Abdulaziz University, ²Independent Scholar, ³School of Health Sciences and Biomedical Engineering, Hebei University of Technology, ⁴School of Engineering, Saveetha University, ⁵Programa de Pós-graduação em Ciência e Engenharia dos Materiais, UFPI

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces <em>In Vitro</em>

11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

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Cited by 1

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2023

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Patricia S. Holt-Torres¹, Yiqing Chen³, Huinan Hannah Liu^1,2,3

¹Microbiology Graduate Program, University of California, Riverside, ²Department of Bioengineering, University of California, Riverside, ³Materials Science & Engineering Program, University of California, Riverside

High-Performance Graphene-Modified Sensing Chip for SARS-CoV-2 Detection

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Cited by 5

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2023

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Parshant Kumar Sharma^1,2,3, Ebrahim Mostafavi^4,5, Nam-Young Kim^1,2,3, Thomas J. Webster⁶, Ajeet Kaushik^7,8

¹RFIC Bio Centre, Kwangwoon University, ²Department of Electronics Engineering, Kwangwoon University, ³NDAC Centre, Kwangwoon University, ⁴Stanford Cardiovascular Institute, Stanford University School of Medicine, ⁵Department of Medicine, Stanford University School of Medicine, ⁶Department of Biomedical Engineering, Hebei University of Technology, ⁷NanoBioTech Laboratory, Department of Environmental Engineering, Florida Polytechnic University, ⁸School of Engineering, University of Petroleum and Energy Studies (UPES)

7:58

Formulation and Characterization of Bioactive Agent Containing Nanodisks

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2023

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Kyle Lethcoe¹, Colin A. Fox¹, Isabel Moh¹, Matthew Swackhamer¹, Michael Karo¹, Ryan Lockhart¹, Robert O. Ryan¹

¹Department of Biochemistry and Molecular Biology, University of Nevada

Abstracts

3D printing of multicellular scaffolds for cardiovascular tissue engineering

Ebrahim Mostafavi^*1

¹Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA

Synthesis of “naked” copper oxide nanoparticles by pulsed laser ablation in liquids

Kidon Sung¹,

Steven Foley¹,

Tina Hesabizadeh²,

Gregory Guisbiers^*2

¹National Center for Toxicological Research, US FDA,

²UA Little Rock

Intracellular Carbon-Based Nanomaterials Characterization Using Electric Force Microscope

Alba Avila^*1,

Homero F Pastrana^*2,

Jaime Andres Perez Taborda³,

Juan Camilo Orozco Cardona⁴

¹Electrical and Electronic Engineering Department: Microelectronic Center (CMUA), Universidad de los Andes, Cra 1E No. 19A-40, Bogotá, Colombia,

² Departamento de Ingeniería Eléctrica y Electrónica, Universidad de Los Andes, Bogotá D.C., Colombia Centro de Microelectrónica, Universidad de los Andes (CMUA), Bogotá D.C, Colombia,

³Grupo de Nanoestructuras y Física Aplicada (NANOUPAR), Universidad Nacional de Colombia Sede De La Paz, La Paz 202010, Colombia,

⁴Centro de Microelectrónica, Universidad de los Andes (CMUA), Bogotá D.C, Colombia