
Biomaterials are substances applied in various fields of medicines that are used to stay in constant contact with body tissues. Tooth filling is considered to be the most practiced example where most people first encounter biomaterials. The other most delicate examples like cardiac repair with heart valves, and joint replacements.
Various categories of biomaterials have been successfully developed. They are used for more than a generation. First-generation biomaterials largely depended on being inert, or relatively inert, with minimal tissue response.
Despite the wide application and its usefulness in human health, nonspecific host immune response is always a challenge to encounter which are prone to infections. Modern biomaterials science provides a large array of biomaterial designs and surface modifications that modulate the host–material interactions to prevent an aggressive foreign-body response and at the same time avoid bacterial colonization. Furthermore, the use of biological motives in the new generations of biomaterials may elicit a specific immune response. Our special issue will cover the following main aspects of the biomaterial application and characterization and proposition of new biomaterial, which could be animal and synthetic origin with less host-tissue immune responses.
• New methods and protocols to develop to characterize the animal, human and synthetic origin tissues
• Interaction of cells and materials in the microenvironment
• Materials as model systems for stem cell growth and modulation into tissue-specific cells
• (Nano)materials and (nano)systems for therapeutic delivery
• Biomimetic materials, including biologically inspired cell-inspired synthetic tools