Thrombosis is at the root of several diseases that kill and affect the quality of life of millions of people worldwide every year. These diseases include life-threatening cardiovascular diseases such as stroke, myocardial infarction, deep vein thrombosis, and its fatal complications like pulmonary embolism. Thus, developing both in vitro and in vivo methods to investigate mechanisms of thrombosis is critically essential for successfully preventing and treating these diseases. Advanced methods are expected to mimic the conditions of human thrombosis, allowing testing of the efficacy of new drugs and methods of combating thrombosis. Standardization of methods used by different labs is another essential aspect of this field of research.

As a result, we are launching this Methods Collection on thrombosis and hemostasis research and inviting researchers from all over the world to contribute their innovative work, demonstrating either new approaches or significant improvement/optimization of existing methods. The collection will include all types of thrombosis, such as arterial, venous, and microvascular thrombosis; thrombosis in the context of diseases (e.g., diabetes mellitus); and models that simulate thrombosis of specific organs (e.g., ischemic stroke). Novel methods for evaluating bleeding tendency will also be addressed. Studies describing in vitro or in vivo methods and new approaches for diagnosing or treating thrombosis-related disorders in the clinical setting are welcome.