
Benjamin Freedman
Wyss Institute for Biologically Inspired Engineering at Harvard University, Beth Israel Deaconess Medical Center, Department of Orthopaedic Surgery, Harvard Medical School
Benjamin Freedman (PhD) is a faculty member in the Department of Orthopedic Surgery at Beth Israel Deaconess Medical Center, where he leads a laboratory focused on the design and synthesis of biomaterials to improve the repair of biological tissues, with a particular focus on the tendon. Ben has received multiple grants from the NIH and NSF to support his research. His laboratory uses novel adhesive hydrogels to bridge the interface between tissues and technology. Collectively, his publications (45 total) have been published in several high-impact journals, including Nature BME, Science Translational Medicine, Advanced Materials, and Science Advances. His research has been covered in over 50 news outlets, presented in over 65 conference abstracts, and resulted in 4 patents as a lead inventor licensed for commercialization. Before starting as a faculty member, Ben completed a postdoctoral fellowship at the Wyss Institute at Harvard University. He holds a PhD in Bioengineering from the University of Pennsylvania and a BS in Biomedical Engineering from the University of Rochester.

Eckhard Weber
Novartis Institutes for BioMedical Research
Eckhard Weber (PhD) is Associate Director at the Novartis Institutes for BioMedical Research (NIBR) in Basel, Switzerland. He leads multidisciplinary, translational research projects dedicated to developing transformative regenerative therapies for tendon diseases. Eckhard collaborates with global scientific leaders from industry and academia across the biomedical and biotechnological universe to integrate innovation in drug discovery, delivery, and development. Joining Novartis in 2000 from academia, Eckhard held senior positions in translational research of different therapeutic areas such as Neuroscience, Arthritis Bone and Metabolism, and Gastrointestinal and Musculoskeletal and directed various projects from drug discovery to clinical development. He holds an MSc and a PhD in Physiology, Biochemistry, and Nutrition from the University of Hohenheim, Germany. Originally from Germany, Eckhard lives in Basel, Switzerland. He is passionate about industrial design, architecture, gardening, and ‘les beaux arts’ in general.
Tendon and ligament diseases are common and devastating, requiring lengthy recovery and resulting in poor tissue regeneration. This Methods Collection will bring together the best contributions from basic and clinical research, emphasizing best practices in innovating, validating, developing, and applying technical and biomedical concepts related to revolutionary therapeutics for tendon/ligament diseases. Relevant papers include, but are not limited to, new avenues in material science, disease modeling (in silico, cellular, organoid, and in vivo), and cutting-edge translational approaches (therapeutic modalities, molecular imaging, data science, clinical outcome measures).
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2024
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Minwei Yang*1, Xiaodi Zou*2, Yaozhao Dong3, Weijie Zhou4, Fangyu Yi5, Sohaib Hasan Abdullah Ezzi6, Vishnu Goutham Kota7, Mohamed Hasan Abdulla Hasan Abdulla7, Haiying Zhou8, Alenikova Olga9, Sahar Ahmed Abdalbary10, Liang Jinhui11, Hui Lu3
1Department of Orthopedics, Hangzhou Ninth People's Hospital, 2Department of Orthopedics, The Second Affiliated Hospital of Zhejiang Chinese Medical University, 3Department of Orthopedics, The First Affiliated Hospital, Zhejiang University, 4Department of Orthopaedics, Joint Service Assurance Force 903 Hospital, 5The First School of Clinical Medicine, Zhejiang Chinese Medical University, 6Department of Orthopaedics, Third Xiangya Hospital, Central South University, 7Zhejiang University School of Medicine, 8School of Biomedical Science, Faculty of Medicine, The Chinese University of Hong Kong, 9Department of Neurology, Republican Research and Clinical Center of Neurology and Neurosurgery, 10Department of Orthopedic Physical Therapy, Faculty of Physical Therapy, Nahda University in Beni Suef, 11Department of Hand Surgery, Xinchang People's Hospital
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2023
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2024
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1Orthopaedic Stem Cell Research Laboratory, Cedars-Sinai Medical Center, 2Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 3Department of Biomedical Sciences, Cedars-Sinai Medical Center, 4Department of Orthopedics, Cedars-Sinai Medical Center, 5Department of Surgery, Cedars-Sinai Medical Center
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2024
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2024
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2024
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Pooja H. Chainani1,2, Patrick M. Williamson1,2, Diana Yeritsyan1, Kaveh Momenzadeh1, Nadim Kheir1, Joseph P. DeAngelis1,3, Arun J. Ramappa1,3, Ara Nazarian1,2,3,4
1Musculoskeletal Translational Innovation Initiative, Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 2Mechanical Engineering Department, Boston University, 3Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 4Department of Orthopaedic Surgery, Yerevan State Medical University
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2024
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2024
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Ana Luísa Graça1, Niklas Kroner-Weigl2, Viviana Reyes Alcaraz1, Sigrid Müller-Deubert1, Maximilian Rudert3, Denitsa Docheva1
1Department of Musculoskeletal Tissue Regeneration, Orthopaedic Hospital König-Ludwig-Haus, University of Würzburg, 2Laboratory for Experimental Trauma Surgery, Department of Trauma Surgery, University Hospital Regensburg, 3Department of Orthopaedics, Orthopaedic Hospital König-Ludwig-Haus, University of Würzburg
A protocol for tendon organoid model
Denitsa Docheva*1
1Julius-Maximilians-University Würzburg