Organ transplantation is a crucial medical procedure that offers the only chance of survival for individuals suffering from organ failure. Despite its life-saving potential, the demand for transplants far exceeds the supply of available organs, resulting in high morbidity and mortality rates. According to the World Health Organization (WHO), only 10% of the global demand for transplantation is currently being met, highlighting the urgent need to increase the number of available transplants.
The shortage of organs for transplant is a complex issue that requires a multi-faceted approach. Increasing the number of transplants has the potential to not only save more lives but also improve the quality of life for individuals suffering from organ failure, while simultaneously reducing healthcare costs associated with prolonged illness and treatment.
This Methods Collection will focus on exploring the implemented strategies for increasing the number of available transplants and investigating future perspectives in this field
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2025
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Pedro Marin-Castro1, Daniel Reis Waisberg1, Rafael Soares Pinheiro1, Liliana Ducatti1, Rodrigo Bronze Martino1, Rubens Macedo Arantes1, Vinicius Rocha-Santos1, Francisco Tustumi2, Luiz Augusto Carneiro-D’Albuquerque1,3, Wellington Andraus1,3
1Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), 2Faculty of Medicine, Department of Gastroenterology - São Paulo, Universidade de São Paulo, 3Laboratory of Medical Investigation 37 (LIM-37), Faculdade de Medicina da Universidade de São Paulo (FMUSP)
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2026
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Intraoperative terlipressin use following normothermic machine perfusion in a porcine liver transplantation model
Nihal Aykun*1
1Duke University
A Reproducible Mouse Orthotopic Liver Transplantation Protocol: Technical Principles and Troubleshooting
Kodai Morimoto1,
Koichiro Uchida*2
1Center for Immune Therapeutics and Diagnosis, Juntendo University,
2Center for Immune Therapeutics and Diagnosis, Juntendo University, Tokyo, Japan