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TOPICAL COLLECTIONS

Advancing Antibacterial Nanobiomaterials: Synthesis, Characterization, Antimicrobial Assays, and AI-Enhanced Design Against Antibiotic-Resistant Bacteria
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Guest Editors

Jonghoon Choi

Jonghoon Choi

Chung-Ang University; Nanomedicine Corporation

Dr. Jonghoon Choi is a full professor in the School of Integrative Engineering at Chung-Ang University. He is also an adjunct professor at the School of Dentistry at Yonsei University. Dr. Choi’s research aims to develop novel nanobiosensors and smart nanobiomaterials for their applications in nanomedicine. Dr. Choi has authored over 125 SCI(E) journal articles, numerous publications, and patent and disclosure applications. His work has been published in top journals, including Nature Nanotechnology, the Journal of Controlled Release, and the Journal of the American Chemical Society. It has been cited >5000 times with an h-index of over 36. Dr. Choi has been an editorial board member for SCI (E) Journals, including PLoS ONE, Analytical Sciences, and Biotechnology & Bioprocess Engineering. Dr. Choi is also the CEO and founder of the Feynman Institute of Technology at the Nanomedicine Corporation, a medical device venture company established in 2020.

Jiyoon Bu

Jiyoon Bu

INHA University

Dr. Jiyoon Bu is an assistant professor in the Department of Biological Engineering at INHA University. His research focuses on the interface of biology, microfluidics, and nanotechnology, aimed at developing novel polymeric nanodevices for biological analysis, diagnostics, and therapeutics. Specifically, his interest lies in comprehending and controlling the biological interactions of polymers with cells at the nanoscale. This fundamental understanding will propel us into translational cancer research fields, encompassing multifunctional liquid biopsy systems for effectively detecting circulating tumor biomarkers and novel drug delivery systems for improved targeting efficacy. Until now, Dr. Bu has authored around 35 peer-reviewed papers in high-profile journals, including Nano Letters, Biomaterials, Advanced Science, Biosensors & Bioelectronics, the Journal of the American Chemical Society, and Advanced Materials. Furthermore, he is listed as a co-inventor on eight filed/pending patents while delivering approximately 100 invited talks and conference presentations. Dr. Bu has also served as an editorial board member or guest editor for various journals, including Oncology Research, Micromachines, and Cancers.

Masayoshi Tanaka

Masayoshi Tanaka

Tokyo Institute of Technology

Dr. Masayoshi Tanaka received the M.Eng. and D.Eng. degrees from the Tokyo University of Agriculture and Technology, Japan, in 2005 and 2008, respectively. In 2009, he was awarded the Newton International Research Fellowship (Royal Society, UK) and worked at the University of Leeds (UK) for two years. In 2011, he became an assistant professor at the Tokyo University of Agriculture and moved to the Tokyo Institute of Technology in 2014. In 2022, he became an associate professor at the Tokyo Institute of Technology. He is the author and co-author of over 80 papers in international refereed journals. His main research interests are to develop new screening techniques for pharmaceutically valuable biomolecules and synthesis technologies for functional nanomaterials by green course.

Toshiki Sawada

Toshiki Sawada

Tokyo Institute of Technology

Dr. Toshiki Sawada is an associate professor in the Department of Chemical Science and Engineering at the Tokyo Institute of Technology. His research pursuits revolve around soft nanomaterials or functional nanomaterials crafted from diverse biopolymers, with a particular emphasis on liquid-crystalline genetically engineered viruses. His portfolio encompasses approximately 90 journal articles, along with an array of publications and patents. His achievements encompass notable accolades such as the MEXT Young Scientists' Prize, bestowed by the Ministry of Education, Culture, Sports, Science, and Technology in Japan; the Award for Encouragement of Research in Polymer Science from The Society of Polymer Science, Japan; The Young Researcher Award from The Society of Fiber Science and Technology, Japan; and the Young Investigator Award from The Japanese Peptide Society.

Collection Overview

In the face of escalating antibiotic resistance, particularly in vulnerable contexts like nosocomial infections such as diabetic foot cases, the urgent need for innovative solutions is evident. Recent research has turned towards nano- and biomaterials as promising candidates for effectively combating antibiotic-resistant bacteria. This Methods Collection is a thorough look at the synthesis, careful analysis, and evaluation of the antimicrobial potential of a wide range of metal nanoparticles, peptides, and other materials or molecules, all of which show promise against bacteria that are resistant to antibiotics.

This curated collection will spotlight pioneering methodologies employing cutting-edge machine learning and AI tools. These advanced techniques hold the key to identifying nanomaterials and biomaterials with the potential to neutralize these resilient bacterial strains. By bridging the gap between traditional approaches and the transformative power of computational intelligence, we aim to empower researchers with innovative insights and methodologies for tackling the pressing challenge of antibiotic-resistant bacteria.

The envisioned impact of this collection extends beyond isolated disciplines, inviting a multidisciplinary audience to engage with the methods presented. By offering a diverse array of techniques, from material design to advanced data-driven strategies, we aspire to catalyze new avenues of research and equip the scientific community with the knowledge needed to develop effective antibacterial interventions. Together, we endeavor to drive progress in the battle against antibiotic-resistant bacteria and inspire collaborative solutions that transcend conventional boundaries.

Articles

Preparation of Zinc Oxide Nanoparticles and the Evaluation of their Antibacterial Effects
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Preparation of Zinc Oxide Nanoparticles and the Evaluation of their Antibacterial Effects

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Cited by 6

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2024

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