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TOPICAL COLLECTIONS

Protocols for Processing Ophthalmic Pathology Specimens
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Guest Editors

Robert M. Verdijk

Robert M. Verdijk

Erasmus MC University Medical Center Rotterdam; The Rotterdam Eye Hospital

Robert M. Verdijk is a senior consultant in ophthalmic pathology and neuropathology at the Erasmus MC University Medical Center, the Leiden University Medical Center, and the Rotterdam Eye Hospital in the Netherlands. He received his training in biomedical sciences and medicine at Leiden University, followed by a Ph.D. in immunology. He did a residency in pathology at the Erasmus MC University Medical Center with a focus on ophthalmic pathology. His research focuses on the pathobiology of ocular malignancy, inflammatory disease, and periorbital xanthogranulomas. He is a member of the editorial board for the WHO Classification of Tumors of the Eye and Orbit (5th edition) and contributed to the WHO Classification of Pediatric Tumors (5th edition). He is a member of the European Ophthalmic Pathology Society (EOPS), president of the working group on ophthalmic pathology of the European Society of Pathology (ESP), and honorary secretary of the Ocular Oncology Group (OOG).

Hardeep Singh Mudhar

Hardeep Singh Mudhar

National Specialist Ophthalmic Pathology Service, Royal Hallamshire Hospital

Dr. Hardeep Singh Mudhar, PhD, FRCPath, is head of the ophthalmic pathology service in the National Specialist Ophthalmic Pathology Service Sheffield laboratory (NSOPS-Sheffield), Dept. of Histopathology, Royal Hallamshire Hospital, UK. He graduated in medicine from Guy’s Hospital Medical School London and the University of Cambridge School of Clinical Medicine, and he did a PhD in developmental biology from University College London. He has practiced as a diagnostic ophthalmic pathologist for 19 years. His main research themes are ocular surface and intraocular tumors, their molecular genetics, and ocular inflammatory diseases. He was involved in editing and authoring several chapters for the WHO Classification of Tumors of the Eye and Orbit for the 4th and upcoming 5th editions. He is a member of the British Association for Ophthalmic Pathology, the European Ophthalmic Pathology Society, and the American Eastern Ophthalmic Pathology Society.

Collection Overview

This Methods Collection aims to enhance the approach for dissecting and processing ophthalmic pathology specimens. Ophthalmologists conduct detailed clinical examinations of the eye in vivo, supplemented by a range of high-resolution imaging modalities. As a result, they rely on high-quality pathology feedback to complete the clinicopathological loop and provide precise prognostic information.

This collection seeks to cover the processing of both larger specimens, such as enucleation and orbital exenteration samples, as well as smaller ones, like pentagonal excisions of the eyelid, conjunctival samples, and corneal specimens. Some of these specimens are relatively small and difficult to handle, with a proven loss rate during processing. The videos in this collection will demonstrate techniques to overcome these challenges. We will present both neoplastic and non-neoplastic pathology specimens for guidance and reference.

Articles

Grossing of Non-neoplastic Globes, Including Fetal Eyes
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Grossing of Non-neoplastic Globes, Including Fetal Eyes

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2025

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