Altered glycosylation is a hallmark of cancer and immunological dysfunction. As a result, it is essential to accurately identify altered glycosylation in silico and the genetic predisposition associated with it. The biological specificity of molecules significantly influences cell physiology and plays a critical role in diagnosis. Over the decades, fundamental biochemical diagnostic methods have evolved into more sophisticated techniques. The traditional antigen-antibody reaction used for blood grouping has progressed to methods like ELISA and, more recently, to flow cytometry, which can precisely detect the presence or absence of receptors or surface molecules. 

This Methods Collection invites submissions of novel methods for the qualitative and quantitative analysis of glycans. These methods aim to address challenges in clinical biochemistry and support diagnostic efforts.