Guest Editor
Collection Overview
The respiratory system is an integral part of the human body, primarily facilitating gas exchange while undertaking several other essential functions. These include immune sensing and defense, protecting against inhaled particles, and maintaining pH balance. Pulmonary disorders are one of the leading causes of morbidity and mortality worldwide. Therefore, it is crucial to establish validated protocols to replicate the physiological and pathological features of human pulmonary disorders accurately.
Advancements in engineering and imaging techniques are continuously refining existing models and developing novel ones. This Methods Collection aims to capture these advancements.
We aim to disseminate protocols that bridge the gap between animal data and human disease. This collection will feature articles detailing state-of-the-art protocols for studying acute and chronic pulmonary diseases, interactions between the pulmonary system and other organs (such as the cardiac and nervous systems), and the influence of environmental factors. We particularly welcome protocols that focus on both upper and lower respiratory tract diseases and disorders, whether acute or chronic, as well as the exacerbation of these conditions by environmental agents and exposures.
Articles
Abstracts
Establishment of a mouse sepsis induced immunosuppression model by intranasal instillation of bacteria
Ling Zeng*1
1Department of Trauma Medical Center, Daping Hospital, State Key Laboratory of Trauma and Chemical Poisoning, Burns and Combined Injury, Army Medical University
Assessment of cardiac relaxation abnormalities using Doppler ultrasonography
Jochen Steppan*1
1Johns Hopkins University