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Innovative Methods in the Study of Viral Infectious Diseases
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Guest Editor

Haojie Hao

Haojie Hao

Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences

Dr. Haojie Hao is an associate professor at the Wuhan Institute of Virology, Chinese Academy of Sciences. He earned his PhD from the same institute in 2019 and conducted postdoctoral research at Shenzhen University. His research focuses on the epitranscriptomic regulation of viral genomes, particularly examining RNA modifications such as N6-methyladenosine (m⁶A), 5-methylcytidine (m⁵C), and N4-acetylcytidine (ac⁴C) in the context of RNA virus replication and antiviral immunity.Dr. Hao has led multiple national and provincial research projects, including studies on Enterovirus 71 and the Nipah virus. He has published his findings in prestigious journals such as Nucleic Acids Research, iScience, and Viruses. His work enhances our understanding of how RNA modifications influence host-virus interactions and opens new avenues for antiviral interventions.

Collection Overview

Viral infectious diseases remain a global health threat, with emerging and re-emerging viruses posing constant challenges to public health and biomedical research. Understanding the molecular mechanisms underlying viral replication, immune evasion, and host response is critical for developing effective diagnostic and therapeutic strategies.


This Methods Collection will bring together cutting-edge protocols and tools used to study viral pathogenesis. It will include methods for viral culture and quantification, infection models, molecular manipulation of viral genomes, analysis of host-virus interactions, and techniques for detecting and interpreting epitranscriptomic modifications in infected cells. The curated collection will serve as a visual and practical guide for researchers and clinicians focused on virology, immunology, and molecular biology, enabling standardization, reproducibility, and innovation in the field.

Articles

Hepatitis E Virus Fluorescence Reduction Neutralization Test for Measuring Neutralizing Antibody Titers
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Hepatitis E Virus Fluorescence Reduction Neutralization Test for Measuring Neutralizing Antibody Titers

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2026

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