Emerging alternative technologies are important elements of society as they convey a novel technological solution to existing societal problems which could not be solved through conventional measures. Regulatory assessment is equally challenging to investigate if they are fit for society. Alternative technologies span a wide range of research fields from novel energy solutions, the popularization of 3D printing in home environments, and the emerging field of e-cigarettes/e-liquids to name a few; which warrants rigorous assessment from a regulatory perspective. The objective of this collection is to make the JoVE Methods journal a common reference point for investigators and policy makers involved in research fields related to alternative technologies. This collection provides a platform for researchers to submit research reports and articles containing Chemianalytic approaches for the assessment of e-cigarette aerosol and/or 3D printing emissions from desktop 3D printers, and handheld 3D pens popular among kids. Methods will span over both custom made and commercial devices for the aerosol emission collection and Chemianalytic characterization of particulate matter. The methods may involve but are not limited to quantifying particle concentration with nanoparticle tracking analysis (NTA) or condensation particle counter (CPC); particle size distribution using dynamic light scattering (DLS), scanning mobility particle sizer (SMP), electron microscopy techniques, or custom based methods; quantitation of metal content into emissions using ICP-M; particle morphology using TEM/SEM; characterization of volatile organic compound (VOCs) emissions; or other alternative methods. We welcome both industry and government research institution to publish in this method collections special issue.