
Affiliation: School of Life Sciences and Biodiscovery Institute, University of Nottingham
Prof. Miguel Cámara is Co-Director of the National Biofilms Innovation Centre (NBIC) working with academic and industrial partners on different areas of biofilm research and innovation. He has many years of expertise in quorum sensing-mediated bacterial cell-cell signalling mechanisms with a particular emphasis on the Cystic Fibrosis opportunistic pathogen Pseudomonas aeruginosa. He has led several drug discovery programs aiming at reducing the impact of antimicrobial resistance through novel anti-virulence target discovery and the design of inhibitors against these, mainly targeting quorum sensing-driven mechanisms.
Some research areas he currently studies on include: (i) identification of novel biomarkers of infection for the development of point of care diagnostics; (ii) molecular mechanisms of biofilm development and adaptation to low oxygen conditions; (iv) identification of novel drugs which prevent biofilm formation or sensitise them to antibiotics; (v) mechanisms of interactions between biofilms and the human host.