Swallowing Disorders

Swallowing disorders, or dysphagia, are conditions that disrupt the safe and efficient movement of food, liquid, or saliva from the mouth to the stomach. Normal swallowing requires coordinated activity across oral, pharyngeal, and esophageal phases, guided by sensory feedback and precisely timed muscle contractions; disruption can cause residue, coughing, choking, or aspiration into the airway. In behavioral research, observing eating patterns, avoidance, distress, and responses to food texture can help distinguish behavioral influences from physiological impairment. Understanding dysphagia supports clinical assessment, safer feeding strategies, rehabilitation, and research on how swallowing affects nutrition, communication, health, and quality of life.

Swallowing Disorders - Related Videos

Research

JoVE Journal - Medicine

Coordinate Mapping of Hyolaryngeal Mechanics in Swallowing

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Cited by 34 •

2014

Coordinate mapping is a method of documenting salient features of hyolaryngeal biomechanics in the pharyngeal phase of swallowing. This methodology uses image analysis software to record coordinates of anatomical landmarks. These coordinates are imported into an excel macro and translated into kinematic variables of interest useful in dysphagia research.

Research

JoVE Journal - Medicine
Free Sample

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

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Cited by 53 •

2015

This study successfully adapted human videofluoroscopic swallowing study (VFSS) methods for use with murine disease models for the purpose of facilitating translational dysphagia research.

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

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2023

This protocol describes a serial transoral laryngoscopy approach for mice and rats that permits close-up, unobstructed video imaging of the larynx during breathing and swallowing using an optimized anesthetic regimen and finely tuned endoscopic manipulation techniques.

Education

JoVE Core - Medical-Surgical Nursing

Upper GI Series: Barium Swallow

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2025

The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues. Purpose and Procedure Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...

Intrinsically Disordered Proteins

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2020

Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...

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