Temperature Receptor Function

Temperature receptor function refers to how sensory receptors detect changes in environmental or body temperature and convert them into neural signals, shaping behavior and physiological regulation. Thermoreceptors use temperature-sensitive ion channels, including members of the transient receptor potential family, whose opening or closing alters membrane potential and changes the firing of sensory neurons. The nervous system integrates these signals to produce responses such as seeking warmth, avoiding heat, adjusting posture, or initiating thermoregulatory processes. Studying this function helps explain temperature preference, heat and cold avoidance, behavioral adaptation, and how organisms maintain stable internal conditions across changing environments.

Temperature Receptor Function - Related Videos

Research

JoVE Journal - Neuroscience

Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors

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Cited by 14 •

2016

Here we present a protocol to describe the localization of angiotensin II Type 1 receptors in the rat brain by quantitative, densitometric, in vitro receptor autoradiography using an iodine-125 labeled analog of angiotensin II.

Fabrication of Microscope Stage for Vertical Observation with Temperature Control Function

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Cited by 3 •

2019

Presented here is a protocol using a temperature-controlled microscope stage that allows a sample container to be mounted on a vertical microscope.

Local Application of Drugs to Study Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices

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Cited by 23 •

2012

In this paper, we describe a useful method to study ligand-gated ion channel function in neurons of acutely isolated brain slices. This method involves the use of a drug-filled micropipette for local application of drugs to neurons recorded using standard patch clamp techniques.

Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes

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Cited by 1 •

2018

Here, we present a protocol for co-immunoprecipitation and an on-bead enzymatic activity assay to simultaneously study the contribution of specific protein domains of plasma membrane receptors to both enzyme recruitment and enzyme activity.

High-throughput Analysis of Mammalian Olfactory Receptors: Measurement of Receptor Activation via Luciferase Activity

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Cited by 16 •

2014

Olfactory receptor activation patterns encode odor identity, but the lack of published data identifying odorant ligands for mammalian olfactory receptors hinders the development of a comprehensive model of odor coding. This protocol describes a method to facilitate high-throughput identification of olfactory receptor ligands and quantification of receptor activation.

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