Dip Cycle Assembly

Dip Cycle Assembly is a bioengineering fabrication method that builds organized multilayer structures through repeated immersion cycles, enabling precise control over material composition and thickness. In each cycle, a substrate is dipped into complementary solutions or suspensions, allowing a selected biological or synthetic component to adsorb before rinsing, drying, or transferring it to the next layer. Repeating these controlled steps produces films, coatings, or scaffold architectures with tunable surface properties and cargo incorporation. The approach supports tissue engineering, biomaterials development, biosensing, and drug delivery by linking nanoscale assembly with macroscopic device performance.

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Research

JoVE Journal - Biology
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Assembly, Loading, and Alignment of an Analytical Ultracentrifuge Sample Cell

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Cited by 21 •

2009

The analytical ultracentrifuge (AUC) sample cell holds sample and reference buffer and during experiments and is exposed to high vacuum and rotor speeds up to 60,000 rpm. This video will demonstrate the rigorous attention to detail necessary for assembly, loading and alignment of this very important component of an AUC experiment.

Education

JoVE Core - Biology

Lytic Cycle of Bacteriophages

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2019

Bacteriophages, also known as phages, are specialized viruses that infect bacteria. A key characteristic of phages is their distinctive “head-tail” morphology. A phage begins the infection process (i.e., lytic cycle) by attaching to the outside of a bacterial cell. Attachment is accomplished via proteins in the phage tail that bind to specific receptor proteins on the outer surface of the bacterium. The tail injects the phage’s DNA genome into the bacterial cytoplasm. In the lytic replication...

What are Biogeochemical Cycles?

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2019

The most common elements in organic molecules, carbon, hydrogen, oxygen, nitrogen, sulfur, and phosphorus, are only available in the ecosystem in limited amounts. Therefore, these nutrients must be recycled through both biotic and abiotic components of the ecosystem, in processes generally called biogeochemical cycles. Biogeochemical Cycles and Decomposition The matter that makes up living organisms, like water, carbon, nitrogen, sulfur and phosphorous, exist in limited quantities within the...

The Water Cycle

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2019

The Earth’s hydrosphere includes all of the areas where the storage and movement of water occurs. Since water is the basis of all living processes, the cycling of water is extremely important to ecosystem dynamics. The water cycle begins as the sun warms surface water on the land and in oceans, causing it to evaporate and enter the atmosphere as vapor. The water vapor condenses into clouds and eventually falls as precipitation in the form of rain, snow or hail. After falling back to the...

The Phosphorus Cycle

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2019

Unlike carbon, water, and nitrogen, phosphorus is not present in the atmosphere as a gas. Instead, most phosphorus in the ecosystem exists as compounds, such as phosphate ions (PO43-), found in soil, water, sediment and rocks. Phosphorus is often a limiting nutrient (i.e., in short supply). Consequently, phosphorus is added to most agricultural fertilizers, which can cause environmental problems related to runoff in aquatic ecosystems. Biological Phosphorus Cycle Phosphorus is present in many...

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