Microalgal Biotechnology
Microalgal Biotechnology - Related Videos
01:59
Plant Breeding and Biotechnology
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2020
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food. As humans' understanding of genetics advanced, improved crop varieties could be achieved more quickly. Artificial selection could be more directed, and crop varieties enhanced for favorable traits more quickly to produce better, more robust, or more palatable plants.
10:17
Analysis of Fucosylated Human Milk Trisaccharides in Biotechnological Context Using Genetically Encoded Biosensors
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Cited by 1 •
2019
We describe here the high-throughput detection and quantification of fucosylated human milk oligosaccharides (HMOs) using a whole-cell biosensor. We also demonstrate here, the adaptation of this platform towards analysis of HMO production strains, focusing on improving the signal to noise ratio.
07:24
Sonication Extraction of Lipid Biomarkers from Sediment
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2023
Source: Laboratory of Jeff Salacup - University of Massachusetts Amherst The material comprising the living "organic" share of any ecosystem (leaves, fungi, bark, tissue; Figure 1) differs fundamentally from the material of the non-living "inorganic" share (rocks and their constituent minerals, oxygen, water, metals). Organic material contains carbon linked to a series of other carbon and hydrogen molecules (Figure 2), which distinguishes it from inorganic material. Carbon's wide valency range...
08:58
Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
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2025
This protocol provides a method for the systematic global optimization of genetically encoded biosensors through automation-assisted genetic library generation and assessment. This is coupled with design-of-experiment methodologies to streamline experimentation and enable the selection of genetic components to tune biosensors to specific design outcomes.
10:18
Ascending Aortic Constriction in Rats for Creation of Pressure Overload Cardiac Hypertrophy Model
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Cited by 17 •
2014
We describe a stepwise procedure for creating pressure overload and left ventricular hypertrophy in Wistar rats by constriction of the ascending aorta using a small metallic clip. This model is extensively used for studying remodeling changes during cardiac hypertrophy and for identifying and evaluating strategies for regression of such changes.
FAQs
These variables regulate photosynthesis and biomass formation in controlled cultivation systems. Light supplies the energy basis for photosynthetic activity, while carbon dioxide and nutrients support cellular growth. Temperature and mixing are additional conditions that influence how effectively the culture develops. Managing these factors together helps bioengineers guide biomass production toward intended downstream uses.
Strain selection and engineering can direct cells toward greater accumulation of particular product classes, including lipids, pigments, proteins, carbohydrates, or other metabolites. This makes the biological platform more adaptable than a single-purpose culture. Bioengineers can therefore match cellular characteristics with goals such as fuel production, food ingredients, pharmaceuticals, or biomaterials.
Metabolic diversity gives microalgae access to multiple value pathways rather than limiting production to one compound. Depending on the strain and cultivation conditions, cells may provide fuels, pigments, proteins, carbohydrates, pharmaceuticals, or biomaterials. That range supports flexible biomanufacturing design, allowing the same general platform to address different product and sustainability objectives.
A typical workflow begins by cultivating a selected or engineered strain under controlled light, carbon dioxide, nutrient, temperature, and mixing conditions. The culture is then directed toward biomass formation or accumulation of a desired cellular product. Finally, the resulting biomass or compounds undergo recovery for use in fuels, ingredients, pharmaceuticals, materials, or other applications.
The platform can produce biofuels, food and feed ingredients, pharmaceuticals, biomaterials, and cellular products such as lipids, pigments, proteins, carbohydrates, and other metabolites. It can also support services including wastewater treatment and carbon utilization. This combination of products and services makes microalgae relevant to both manufacturing systems and environmental biotechnology.
Microalgal biotechnology connects photosynthetic biology with bioengineering by using controlled cultivation and strain selection or engineering to guide production. Rapid growth, metabolic diversity, and the ability to use nonarable resources support alternative production systems. Its relevance extends beyond product synthesis because platforms can also address wastewater treatment and carbon utilization within sustainability-oriented designs.