Platinum Release
Platinum Release - Related Videos
07:20
Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Cited by 1 •
2014
This protocol describes the use of amide coupling reactions of isonicotinic acid and diaminoalkanes to form bridging ligands suitable for use in the synthesis of multinuclear platinum complexes, which combine aspects of the anticancer drugs BBR3464 and picoplatin.
08:32
Electrochemical Roughening of Thin-Film Platinum Macro and Microelectrodes
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2019
This protocol demonstrates a method for electrochemical roughening of thin-film platinum electrodes without preferential dissolution at grain boundaries. The electrochemical techniques of cyclic voltammetry and impedance spectroscopy are demonstrated to characterize these electrode surfaces.
09:02
Synthesis of Platinum-nickel Nanowires and Optimization for Oxygen Reduction Performance
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2018
The protocol describes the synthesis and electrochemical testing of platinum-nickel nanowires. Nanowires were synthesized by the galvanic displacement of a nickel nanowire template. Post-synthesis processing, including hydrogen annealing, acid leaching, and oxygen annealing were used to optimize nanowire performance and durability in the oxygen reduction reaction.
09:37
Dopamine Release at Individual Presynaptic Terminals Visualized with FFNs
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Cited by 10 •
2009
A new means to measure neurotransmission optically using fluorescent dopamine analogs.
01:28
Energy-releasing Steps of Glycolysis
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2019
Glycolysis is divided into two phases based on whether energy is utilized or released. While the first phase consumes ATP, the second phase produces energy in the form of ATP and NADH. The energy is released over a sequence of reactions that turns G3P into pyruvate. The energy-releasing phase—steps 6-10 of glycolysis—occurs twice, once for each of the two 3-carbon sugars produced during steps 1-5 of the first phase. The first energy-releasing step—the 6th step of glycolysis —consists of two...
FAQs
Material composition determines which platinum-containing species are available for liberation, while surface chemistry governs how readily the surrounding environment interacts with the solid. These factors can change the rate and overall profile of release, making them important design variables when developing platinum-containing implants, electrodes, catalysts, or drug-delivery systems.
The surrounding fluid, pH, temperature, and exposure time can substantially affect the amount and rate of platinum becoming available. Because these variables interact with the material surface and composition, changing them may produce different release profiles. Controlling them during evaluation helps researchers distinguish material behavior from effects caused by the test environment.
Dissolution, corrosion, and degradation describe different routes through which a solid material can lose platinum or platinum-containing compounds to its surroundings. The dominant process depends on the material and exposure conditions. Identifying which process controls release helps researchers interpret changes in material stability and anticipate how performance may evolve during use.
A basic evaluation exposes the platinum-containing material to a defined surrounding fluid for a specified period while controlling relevant conditions such as pH and temperature. Researchers then assess the platinum released across the exposure interval and organize the results as a release profile. Comparing profiles under different conditions reveals how the material behaves.
Release profiles show how platinum availability changes with exposure time and environmental conditions. Researchers can use these patterns to evaluate material stability and biocompatibility, rather than relying only on the material’s initial composition. The results also help identify designs that may provide more predictable biological or therapeutic responses in biomedical applications.
In bioengineering, release analysis supports decisions about platinum-containing implants, electrodes, catalysts, and drug-delivery systems. Researchers can relate the observed profile to material performance, stability, and potential biological effects. This context is especially valuable when designing systems that must behave predictably in surrounding fluids and maintain an appropriate balance between function and biocompatibility.