Porcine Spine Model
Porcine Spine Model - Related Videos
09:07
An Anesthesia, Surgery, and Harvest Method for the Evaluation of Transpedicular Screws Using an In Vivo Porcine Lumbar Spine Model
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2017
Here, we introduce a method to evaluate transpedicular screws by using an in vivo porcine lumbar spine model.
03:02
Intrathecal Placement of Lumbar Drain: A Technique to Withdraw Cerebrospinal Fluid from the Lumbar Spine in Porcine Model
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2025
This video describes the technique of intrathecal placement of a lumbar drain in a porcine ischemic model, which helps in draining the cerebrospinal fluid to a drainage system. The cerebrospinal fluid pressure is monitored by the drainage system, and fluid is drained to maintain a constant cerebrospinal fluid pressure.
05:28
A Mouse Model of Lumbar Spine Instability
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Cited by 14 •
2021
We developed a lumbar intervertebral disc degeneration mouse model by resection of L3–L5 spinous processes along with supra- and inter-spinous ligaments and detachment of paraspinous muscles.
02:49
Harvesting DRG from Rat Spine: A Procedure to Extract Dorsal Root Ganglion from the Spine of a Rat Model
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2023
In this video, we demonstrate the extraction of dorsal root ganglion or DRG from a harvested rat spine for downstream applications.
11:47
Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
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Cited by 24 •
2016
Porcine models of organ transplantation provide an important platform to study mechanisms of organ preservation. This article describes a heterotopic porcine renal autotransplantation model, which allows investigating new approaches to improve the outcome of transplantation using marginal kidney grafts.
FAQs
Controlled mechanical loading exposes vertebrae, intervertebral discs, or intact spinal segments to defined forces or motion. Researchers then assess outcomes such as stability, pressure, stiffness, and tissue behavior. Comparing these responses under controlled conditions helps identify how spinal structures react to mechanical demands, injury, degeneration, or surgical manipulation.
These components provide different experimental levels for studying spinal structure and function. Individual vertebrae or discs can support focused analysis of tissue behavior, while intact segments preserve interactions among spinal structures during loading or motion. Selecting the appropriate preparation allows bioengineers to match the model to questions about stability, pressure, stiffness, or tissue response.
Defined conditions make mechanical loading, motion, injury, degeneration, and surgical manipulation more controlled and interpretable. Laboratory studies can support systematic measurement of spinal responses, whereas in vivo conditions provide another setting for examining tissue behavior. This distinction helps researchers connect observed changes to the experimental environment and the intended bioengineering question.
Researchers can subject spinal specimens or segments to controlled loading, motion, or surgical manipulation after introducing an implant or fixation system. Measurements of stability, pressure, stiffness, and tissue behavior provide evidence of how the tested device affects spinal mechanics. These results support comparative evaluation before later stages of clinical translation.
The model can support measurement of changes in stability, pressure, stiffness, and tissue behavior. These outcomes describe both mechanical performance and responses of spinal tissues under specified conditions. Together, they help researchers assess the effects of loading, motion, injury, degeneration, or surgical manipulation and determine whether a tested strategy produces the intended change.
In bioengineering, porcine spine models connect controlled bench investigations with questions relevant to eventual clinical use. They support evaluation of implants, fixation systems, biomaterials, imaging methods, and regenerative strategies. By generating measurements under defined laboratory or in vivo conditions, the models help characterize performance and tissue responses before researchers pursue clinical translation.