Porous Silicon Film
Porous Silicon Film - Related Videos
01:44
Sustained Delivery of Nerve Growth Factor Using a Porous Silicon Film in Rat Pheochromocytoma 12 Cells
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2025
Source: Rosenberg, M., et al. Designing Porous Silicon Films as Carriers of Nerve Growth Factor. J. Vis. Exp. (2019).This video demonstrates the use of a degradable nanostructured porous silicon (PSi) film for the sustained release of nerve growth factor (NGF) to support PC12 cell differentiation. NGF is adsorbed onto the film’s pores through electrostatic interactions and is gradually released into the media by diffusion and scaffold degradation. This controlled delivery promotes PC12 cell...
10:12
Designing Porous Silicon Films as Carriers of Nerve Growth Factor
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Cited by 3 •
2019
Here, we present a protocol to design and fabricate nanostructured porous silicon (PSi) films as degradable carriers for the nerve growth factor (NGF). Neuronal differentiation and outgrowth of PC12 cells and mice dorsal root ganglion (DRG) neurons are characterized upon treatment with the NGF-loaded PSi carriers.
06:53
Fabrication and Optimization of Type II Silicon Clathrate Films
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2025
The two-thermal annealing method enables the fabrication of thin films of type II semiconductor silicon clathrate. Post-synthesis treatments, including thermal pressing and reactive ion etching, were performed to improve the material properties. This approach provides an accessible pathway for fabricating tunable clathrate films suitable for next-generation electronic and photonic devices.
07:37
Preparation of Macroporous Epitaxial Quartz Films on Silicon by Chemical Solution Deposition
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Cited by 7 •
2015
A protocol is presented for the preparation of piezoelectric macroporous epitaxial films of quartz on silicon by solution chemistry using dip-coating and thermal treatments in air.
09:32
Polycrystalline Silicon Thin-film Solar cells with Plasmonic-enhanced Light-trapping
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Cited by 9 •
2012
Polycrystalline silicon thin-film solar cells on glass are fabricated by deposition of boron and phosphorous doped silicon layers followed by crystallisation, defect passivation and metallisation. Plasmonic light-trapping is introduced by forming Ag nanoparticles on the silicon cell surface capped with a diffused reflector resulting in ~45% photocurrent enhancement.
FAQs
Electrochemical etching selectively dissolves silicon, creating the film’s pore network rather than simply removing material uniformly. By adjusting etching conditions, researchers can tune pore size, porosity, and film thickness. Those structural parameters determine how much internal surface is available and how substances can move through the film, making fabrication conditions central to its bioengineering performance.
Surface oxidation and chemical functionalization change how the silicon surface interacts with biological molecules. These treatments provide a post-fabrication way to tailor the interface without relying only on pore structure. In practice, the modified surface can support biomolecular binding in sensing systems or adjust interactions at interfaces used for cell studies and implantable devices.
Porous silicon film biosensors can translate biomolecular binding into measurable optical or electrical changes. The interconnected pores provide a high-area interface where binding events can influence the film’s signal, while tunable transport affects access to that interface. This combination is useful when a device must couple molecular interactions with a readable physical output.
For drug-loading and release platforms, pore structure and surface chemistry are key design features. Porosity and pore dimensions support loading within the film, while tunable transport and chemical modification can adjust interactions inside the material. The resulting platform can therefore be customized for controlled release rather than being limited to one fixed delivery behavior.
A typical workflow begins by electrochemically etching silicon to form a film with selected pore size, porosity, and thickness. Researchers can then apply surface oxidation or chemical functionalization to modify biological interactions. The prepared film is subsequently configured for a target use, such as biomolecular sensing, drug loading, cell-interaction studies, or an implantable device interface.
In bioengineering, this material platform supports several distinct objectives: detecting biomolecular binding, carrying and releasing drugs, examining how cells respond to a customizable surface, and building implantable device interfaces. Its value comes from combining adjustable structure with adjustable surface chemistry, allowing the film to be adapted to the biological interaction or transport requirement being studied.