Crossed Extensor Reflex

The crossed extensor reflex is a protective spinal cord response that withdraws a limb from a painful stimulus while maintaining balance and support. Nociceptors activate sensory neurons that relay signals through spinal interneurons, exciting flexor muscles and inhibiting ipsilateral extensors, while commissural interneurons produce the opposite pattern in the contralateral limb by activating extensors and inhibiting flexors. This polysynaptic reflex coordinates rapid, automatic movements and helps prevent falls during withdrawal. Studying it clarifies how the spinal cord integrates sensory information, organizes coordinated motor output, and contributes to locomotion, posture, and neurological assessment.

Crossed Extensor Reflex - Related Videos

Research

JoVE Journal - Neuroscience
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Physiological Recordings of High and Low Output NMJs on the Crayfish Leg Extensor Muscle

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Cited by 13 •

2010

This article demonstrates how to conduct electrophysiological recordings of synaptic responses on the extensor muscle in the walking leg of a crayfish and how the nerve terminals are visualized to show the gross morphological differences of high- and low-output nerve terminals.

Research

JoVE Journal - Behavior

Neurodevelopmental Reflex Testing in Neonatal Rat Pups

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Cited by 77 •

2017

Behavioral testing is the gold standard for determining outcomes following brain injury, and can identify the presence of developmental disabilities in infants and children. Neurodevelopmental reflexes are an early indicator of these abnormalities. A host of easily accomplished developmental reflex tests in the neonatal rodent were developed and described here.

Education

JoVE Core - Anatomy and Physiology

Reflex Activity

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2024

A reflex activity is an automatic, involuntary response to specific stimuli. It is a part of our survival mechanism, designed to protect us from potential harm. For example, when a bright light suddenly shines into our eyes, we instinctively close them or look away. This is a simple reflex activity orchestrated by the nervous system without conscious thought or effort. A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...

The Micturition Reflex

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2024

Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying. The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating urine...

Early Reflexes During Infancy

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2026

Early reflexes are automatic, involuntary responses to specific stimuli and provide information about neurological development during infancy. Some reflexes are present at birth or appear soon afterward. Known as primitive reflexes, they support early survival and adaptation.Primitive ReflexesPrimitive reflexes help newborns respond to their environment before voluntary motor control develops. The rooting reflex causes an infant to turn toward stimulation near the mouth, helping the infant...

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