Dural Venous Sinuses

Dural venous sinuses are endothelial-lined channels between layers of the cranial dura mater that drain deoxygenated blood and cerebrospinal fluid from the brain. Unlike typical veins, they have rigid walls formed by dural separation and lack valves, allowing blood to flow through interconnected pathways toward the internal jugular veins. Major sinuses, including the superior sagittal, straight, transverse, and sigmoid sinuses, collect blood from cerebral veins and receive cerebrospinal fluid through arachnoid granulations. Their anatomy supports intracranial circulation and pressure regulation, while obstruction or thrombosis can impair drainage and cause serious neurological complications.

Dural Venous Sinuses - Related Videos

Research

JoVE Journal - Neuroscience

Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis

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2025

This study presents a protocol for establishing a reproducible, minimally invasive rat model of superior sagittal sinus thrombosis induced by ferric chloride, utilizing a silk-suture method in combination with laser speckle contrast imaging and high-resolution ultrasound for evaluation.

Education

JoVE Science Education - Clinical Skills

Nose, Sinuses, Oral Cavity and Pharynx Exam

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2023

Source: Richard Glickman-Simon, MD, Assistant Professor, Department of Public Health and Community Medicine, Tufts University School of Medicine, MA This video provides an overview of sinus, nose, and throat examinations. The demonstration begins with a brief overview of the anatomy of the region. The upper third of the nose is bony, and the bottom two-thirds are cartilaginous. Air entering the nares passes through the nasal vestibules and into the narrow passageway between the nasal septum...

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

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Cited by 9 •

2013

The objective of this research is to recreate and then access the anatomy of the human cardiac venous system using 3D reconstructions generated from contrast-computed tomography scans.

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus

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Cited by 51 •

2013

We describe procedures to quantify and characterize atherosclerotic lesions in mouse models using precision sectioning of the aortic sinus and ascending aorta combined with histochemical and immunohistochemical analysis.

Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.

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Cited by 13 •

2015

We describe a method for creating a reliable model of cerebral venous hypertension in the adult mouse. This model has been widely described and tested in the rat. This new counterpart in the mice opens the possibility of using genetic modified animals and thereby broadens the applications of the model.

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