Follicular Phase

The follicular phase is the first part of the ovarian, or menstrual, cycle, beginning with menstruation and ending at ovulation. During this phase, follicle-stimulating hormone (FSH) promotes the growth of ovarian follicles, while granulosa cells produce increasing estradiol and inhibin B; as hormone levels change, one dominant follicle is selected and prepares to release an oocyte. The follicular phase helps coordinate ovarian activity with changes in the uterine lining and provides a framework for understanding reproductive timing, fertility, and endocrine regulation. Studying its hormonal patterns supports research into ovulation disorders, contraceptive development, assisted reproduction, and menstrual health.

Follicular Phase - Related Videos

Research

JoVE Journal - Medicine

Collection of Human Follicular Fluid, Follicle Somatic Cells, and Immature Oocytes from Individuals Undergoing In Vitro Fertilization

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2025

This protocol outlines standardized methods to isolate and process follicular fluid, somatic cells, and immature oocytes from IVF procedures, enabling high-quality molecular and cellular analyses. These approaches support translational research into fertility, reproductive aging, and ovarian dysfunction using materials typically discarded in clinical care.

Xenopus Oocytes: Optimized Methods for Microinjection, Removal of Follicular Cell Layers, and Fast Solution Changes in Electrophysiological Experiments

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Cited by 5 •

2016

Optimized procedures for the isolation of single follicles, cytoplasmic RNA microinjections, the removal of surrounding cell layers, and protein expression in Xenopus oocytes are described. In addition, a simple method for fast solution changes in electrophysiological experiments with ligand-gated ion channels is presented.

Education

JoVE Core - Chemistry

Phase Diagrams

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2020

A phase diagram combines plots of pressure versus temperature for the liquid-gas, solid-liquid, and solid-gas phase-transition equilibria of a substance. These diagrams indicate the physical states that exist under specific conditions of pressure and temperature and also provide the pressure dependence of the phase-transition temperatures (melting points, sublimation points, boiling points). Regions or areas labeled solid, liquid, and gas represent single phases, while lines or curves represent...

Phase Transitions

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2020

Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to occupy...

Single Phase Inverter

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2023

Source: Ali Bazzi, Department of Electrical Engineering, University of Connecticut, Storrs, CT. DC power is unidirectional and flows in one direction, whereas, AC current alternates directions at a frequency of 50-60 Hz. Most common electronic devices are designed to run off of AC power; therefore an input DC source must be inverted to AC. Inverters convert DC voltage to AC through switching action that repeatedly flips the polarity of the input DC source at the output or load side for part of...

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