Gastrointestinal System
Gastrointestinal System - Related Videos
08:15
Gastrointestinal Motility Monitor (GIMM)
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Cited by 36 •
2010
Evaluation of colonic motility in the guinea pig distal colon with the Gastrointestinal Motility Monitor (GIMM) is a straightforward and simple to learn approach to quantitatively evaluate propulsive motility in the gastrointestinal tract.
06:02
Isolation of CD 90+ Fibroblast/Myofibroblasts from Human Frozen Gastrointestinal Specimens
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Cited by 17 •
2016
Here, a protocol to isolate and establish primary fibroblast/myofibroblast (MF) cultures from frozen gastric, small intestinal, and colonic tissue-yielding cells with a MF phenotype-is presented. These cells express CD90, α-SMA and vimentin. MFs can be used for a variety of functional assays including enzymatic activity and cytokine production.
01:26
Anatomy of the Gastrointestinal System
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2025
The human digestive system is an intricate and essential network for nutrient absorption and waste elimination. It encompasses the gastrointestinal (GI) tract and several accessory organs. Here's a detailed walkthrough of this complex system: Oral Cavity: The starting point of the digestive process. It comprises lips, cheeks, teeth, and salivary glands within mucous membranes. It extends to the soft palate, the floor of the mouth, and the tongue. Pharynx: It is a tubular...
06:04
Ex Vivo Intestinal Sacs to Assess Mucosal Permeability in Models of Gastrointestinal Disease
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Cited by 41 •
2016
This protocol describes the use of excised intestinal tissue preparations or "intestinal sacs" as an ex vivo model of intestinal barrier function. This model may be used to assess integrity of both the epithelial barrier and the mucous gel layer at specific intestinal sites in animal models of digestive disease.
08:22
Using an Ingestible Telemetric Temperature Pill to Assess Gastrointestinal Temperature During Exercise
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Cited by 32 •
2015
This study describes an accurate, reliable and non-invasive technique to continuously measure gastrointestinal temperature during exercise. The ingestible telemetric temperature pill is suitable to measure gastrointestinal temperature in laboratory settings as well as in field based settings.
FAQs
Coordinated muscle contractions propel food through the digestive tract while also mixing it with digestive substances. This movement exposes food to enzymes, acid, bile, and intestinal secretions, allowing chemical breakdown to occur more effectively. The sequence from the mouth through the intestines supports orderly processing rather than simultaneous, unregulated passage through every organ.
These substances contribute to chemical digestion by acting on complex food molecules under different conditions along the tract. Acid and enzymes participate in processing within the stomach, while bile and intestinal secretions support later breakdown in the intestine. Their coordinated activity converts food into components that can be transferred into circulation.
The small intestine is the principal site where digestion products move into the circulation. Its position after stomach processing allows nutrients released from complex food molecules to be transferred after chemical breakdown has occurred. This function directly connects gastrointestinal activity with energy balance, growth, and the body’s ongoing access to absorbed nutrients.
The small intestine primarily handles the transfer of digested nutrients into circulation, whereas the large intestine reclaims water and supports microbial activity. This division of labor helps the body recover useful materials while processing what remains after nutrient absorption. Comparing these regions clarifies why intestinal dysfunction can affect nutrition, hydration, or waste handling in different ways.
Food passes through the mouth, esophagus, stomach, small intestine, and large intestine before indigestible material is eliminated. Along this route, mechanical mixing and muscle contractions accompany exposure to acid, enzymes, bile, and intestinal secretions. Following the sequence helps researchers and students relate each organ’s position to the digestive or absorptive task it supports.
Its functions provide a framework for examining how nutrition supports energy balance and growth, while abnormalities can help explain digestive disorders. Study also extends to interactions between the host and intestinal microbes, as well as approaches to disease diagnosis and treatment. These applications connect biological mechanisms with clinical questions about health and disease.